The effect of pseudoknot base pairing on cotranscriptional structural switching of the fluoride riboswitch

LM Hertz, EN White, K Kuznedelov… - Nucleic acids …, 2024 - academic.oup.com
A central question in biology is how RNA sequence changes influence dynamic
conformational changes during cotranscriptional folding. Here we investigated this question …

Modulation of Biomolecular Liquid–Liquid Phase Separation by Preferential Hydration and Interaction of Small Osmolytes with Proteins

K Kitamura, A Oshima, F Sasaki… - The Journal of …, 2024 - ACS Publications
We examined the effects of trimethylamine N-oxide (TMAO) and urea (known osmolytes) on
the liquid–liquid phase separation (LLPS) of fused in sarcoma (FUS) and three FUS-LLPS …