Systematic review and meta-analysis of predictors of post-thyroidectomy hypocalcaemia

O Edafe, R Antakia, N Laskar, L Uttley… - Journal of British …, 2014 - academic.oup.com
Background Hypocalcaemia is common after thyroidectomy. Accurate prediction and
appropriate management may help reduce morbidity and hospital stay. The aim of this study …

Actin-based cell protrusion in a 3D matrix

PT Caswell, T Zech - Trends in cell biology, 2018 - cell.com
Cell migration controls developmental processes (gastrulation and tissue patterning), tissue
homeostasis (wound repair and inflammatory responses), and the pathobiology of diseases …

Tenascin C in metastasis: A view from the invasive front

CM Lowy, T Oskarsson - Cell adhesion & migration, 2015 - Taylor & Francis
The extracellular matrix protein tenascin C (TNC) is a large glycoprotein expressed in
connective tissues and stem cell niches. TNC over-expression is repeatedly observed in …

Fascin regulates nuclear movement and deformation in migrating cells

A Jayo, M Malboubi, S Antoku, W Chang… - Developmental cell, 2016 - cell.com
Fascin is an F-actin-bundling protein shown to stabilize filopodia and regulate adhesion
dynamics in migrating cells, and its expression is correlated with poor prognosis and …

Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?

H Liu, Y Zhang, L Li, J Cao, Y Guo, Y Wu… - Molecular Therapy …, 2021 - cell.com
Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

Hypoxia-inducible factor-1 promotes pancreatic ductal adenocarcinoma invasion and metastasis by activating transcription of the actin-bundling protein fascin

X Zhao, S Gao, H Ren, W Sun, H Zhang, J Sun, S Yang… - Cancer research, 2014 - AACR
Because of the early onset of local invasion and distant metastasis, pancreatic ductal
adenocarcinoma (PDAC) is the most lethal human malignant tumor, with a 5-year survival …

Mechanical cues affect migration and invasion of cells from three different directions

CT Mierke - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Cell migration and invasion is a key driving factor for providing essential cellular functions
under physiological conditions or the malignant progression of tumors following downward …

Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization

FK Huang, S Han, B Xing, J Huang, B Liu… - Nature …, 2015 - nature.com
One of the key steps during tumour metastasis is tumour cell migration and invasion, which
require actin cytoskeletal reorganization. Among the critical actin cytoskeletal protrusion …

Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas

K Wu, X Zhang, F Li, D Xiao, Y Hou, S Zhu, D Liu… - Nature …, 2015 - nature.com
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is
largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis …

Effectiveness of preventative and other surgical measures on hypocalcemia following bilateral thyroid surgery: a systematic review and meta-analysis

R Antakia, O Edafe, L Uttley, SP Balasubramanian - Thyroid, 2015 - liebertpub.com
Background: A variety of measures have been proposed to reduce the incidence of post-
thyroidectomy hypocalcemia. The aim of this study was to perform a systematic review and …