Inherited and age-related retinal degeneration is the hallmark of a large group of
heterogeneous diseases and is the main cause of untreatable blindness today. Genetic …

Presence of a fovea centralis is directly linked to molecular specification of an avascular
area in central retina, before the fovea (or 'pit') begins to form. Modelling suggests that …

Although imaging of the living retina with adaptive optics scanning light ophthalmoscopy
(AOSLO) provides microscopic access to individual cells, such as photoreceptors, retinal …

A broadband adaptive optics scanning ophthalmoscope (BAOSO) consisting of four afocal
telescopes, formed by pairs of off-axis spherical mirrors in a non-planar arrangement, is …

Purpose To report the results after 4 years of follow-up in a previously presented first case of
induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) sheet …

A quarter century ago, we were limited to a macroscopic view of the retina inside the living
eye. Since then, new imaging technologies, including confocal scanning laser …

Methods.: Twelve patients were enrolled. All patients underwent a complete ocular
examination, spectral-domain optical coherence tomography (SD-OCT), full-field …

Purpose.: We described anatomic age-related changes in the human eye to determine
potential areas of investigation that may lead to identifying eyes at risk for age-related …

Purpose.: Albinism is associated with disrupted foveal development, though intersubject
variability is becoming appreciated. We sought to quantify this variability, and examine the …

Purpose: To evaluate how metrics used to describe the cone mosaic change in response to
simulated photoreceptor undersampling (ie, cell loss or misidentification). Methods: Using …