Double knockout Nme1/Nme2 mouse model suggests a critical role for NDP kinases in erythroid development
EH Postel, X Zou, DA Notterman… - Molecular and cellular …, 2009 - Springer
Nm23/NDP kinases A and B encoded by the Nme1/Nme2 genes are multifunctional
enzymes responsible for the majority of NDP kinase activity in mammals. This review …
enzymes responsible for the majority of NDP kinase activity in mammals. This review …
Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives
Substantial effort has been directed at elucidating the functions of the products of the Nm23
tumor metastasis suppressor genes over the past two decades, with the ultimate goal of …
tumor metastasis suppressor genes over the past two decades, with the ultimate goal of …
Cell-permeable NM23 blocks the maintenance and progression of established pulmonary metastasis
J Lim, G Jang, S Kang, G Lee, DTT Nga, DTL Phuong… - Cancer research, 2011 - AACR
Occult metastases are a major cause of cancer mortality, even among patients undergoing
curative resection. Therefore, practical strategies to target the growth and persistence of …
curative resection. Therefore, practical strategies to target the growth and persistence of …
Proteomic profiling of rat bone marrow mesenchymal stem cells induced by 5-azacytidine
NS Ye, J Chen, GA Luo, RL Zhang… - Stem Cells and …, 2006 - liebertpub.com
Mesenchymal stem cells (MSCs) can differentiate into different types of cells and thus have
tremendous potential for cell therapy and tissue engineering. 5-Azacytidine (5-aza), a DNA …
tremendous potential for cell therapy and tissue engineering. 5-Azacytidine (5-aza), a DNA …
Methylene ATP analogs as modulators of extracellular ATP metabolism and accumulation
SM Joseph, MA Pifer, RJ Przybylski… - British journal of …, 2004 - Wiley Online Library
Transient accumulation of extracellular ATP reflects both release of ATP from intracellular
stores and altered rates of ATP metabolism by ecto‐enzymes. Ecto‐nucleoside triphosphate …
stores and altered rates of ATP metabolism by ecto‐enzymes. Ecto‐nucleoside triphosphate …
Targeted deletion of Nm23/nucleoside diphosphate kinase A and B reveals their requirement for definitive erythropoiesis in the mouse embryo
EH Postel, I Wohlman, X Zou, T Juan… - … dynamics: an official …, 2009 - Wiley Online Library
The ubiquitously expressed nucleoside diphosphate kinases (Nm23/NDPK/Awd) are a large
family of multifunctional enzymes implicated in nucleic acid metabolism and in normal and …
family of multifunctional enzymes implicated in nucleic acid metabolism and in normal and …
Extracellular NM23 protein promotes the growth and survival of primary cultured human acute myelogenous leukemia cells
J Okabe‐Kado, T Kasukabe, Y Honma… - Cancer …, 2009 - Wiley Online Library
An elevated serum level of NM23‐H1 protein is found in acute myelogenous leukemia
(AML), and predicts a poor treatment outcome in AML patients. To investigate the potential …
(AML), and predicts a poor treatment outcome in AML patients. To investigate the potential …
Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone
Nm23-H1 plays complex roles in the development of diverse cancers including breast
carcinoma, high-grade lymphomas, and acute myeloid leukemia (AML). In the case of AML …
carcinoma, high-grade lymphomas, and acute myeloid leukemia (AML). In the case of AML …
Regulators affecting the metastasis suppressor activity of Nm23-H1
HD Kim, BH Youn, TS Kim, SH Kim, HS Shin… - Molecular and cellular …, 2009 - Springer
Nm23-H1 encodes nucleoside diphosphate kinase A (NDPK-A) and is known to have a
metastasis suppressive activity in many tumor cells. However, it has many other functions as …
metastasis suppressive activity in many tumor cells. However, it has many other functions as …
Nm23-H1 regulates the proliferation and differentiation of the human chronic myeloid leukemia K562 cell line: a functional proteomics study
L Jin, G Liu, C Zhang, C Lu, S Xiong, MY Zhang, QY Liu… - Life sciences, 2009 - Elsevier
AIMS: Nm23-H1 is a suppressor of metastasis that has been implicated in the regulation of
proliferation and differentiation of hematopoietic cells, although specific mechanisms for …
proliferation and differentiation of hematopoietic cells, although specific mechanisms for …