T cells play a critical role in the pathogenesis of systemic lupus erythematosus (SLE), which
is a severe autoimmune disease. In the past 60 years, only one new therapeutic agent with …

We aimed to perform a structured literature review of spinal radiographic progression, as
assessed by the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS), in patients …

Objective To investigate the efficacy and safety of brodalumab, a fully human anti-interleukin-
17 receptor A monoclonal antibody, in patients with axial spondyloarthritis (axSpA). Methods …

Spondyloarthritiden (SpA) sind entzündlich rheumatische Erkrankungen, die durch
Entzündungen im Bereich der Wirbelsäule gekennzeichnet sind, welche häufig zu …

Objectives While many axSpA patients, eligible to receive anti-TNFα therapy, derive benefit
when prescribed them, some patients do not. The current study aims to identify modifiable …

Biological disease-modifying antirheumatic drugs (bDMARDs) are highly effective agents for
the treatment of inflammatory arthritis; however, they also possess a potential risk for serious …

Objective T cells play a critical role in the pathogenesis of systemic lupus erythematosus
(SLE). Serum‐derived exosomes are increased in SLE patients and are correlated with …

Objective To evaluate similarities and differences between non-radiographic axial
spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS) with regard to treatment effects …

Objective To evaluate the long‐term clinical and imaging efficacy of etanercept in patients
with early, active nonradiographic axial spondyloarthritis (SpA). Methods Adult patients who …

Background: Biologic drugs, introduced in clinical practice almost twenty years ago,
represent nowadays a prominent treatment option in patients with chronic inflammatory …