Detection of cytomegalovirus nucleic acid sequences in pancreas in type 2 diabetes
JM Lohr, MBA Oldstone - The Lancet, 1990 - Elsevier
Nucleic acid sequences specific for human cytomegalovirus (CMV) were found in samples
of pancreatic tissue from patients with non-insulin-dependent (type 2) diabetes mellitus …
of pancreatic tissue from patients with non-insulin-dependent (type 2) diabetes mellitus …
An incidence peak of juvenile diabetes. Relation to Coxsackie B virus immune response
G Friman, J Fohlman, G Frisk, H Diderholm… - Acta …, 1985 - Wiley Online Library
All new eases of insulin dependent diabetes mellitus (IDDM) in children below 15 years of
age were recorded prospectively during a 21–year period 1964–1984 in a defined uptake …
age were recorded prospectively during a 21–year period 1964–1984 in a defined uptake …
Human cytomegalovirus in the pancreas of patients with type 2 diabetes: is there a relation to clinical features, mRNA and protein expression of insulin, somatostatin …
M Löhr, B Bergstrome, R Maekawa, MBA Oldstone… - Virchows Archiv A, 1992 - Springer
Human cytomegalovirus (HCMV) was recently demonstrated in the pancreas of about half
the patients with type 2 diabetes mellitus in the absence of mumps, rubella or Coxsackie B …
the patients with type 2 diabetes mellitus in the absence of mumps, rubella or Coxsackie B …
Diabetogenic potential of coxsackie B viruses in nature
GW Jordan, V Bolton, NJ Schmidt - Archives of virology, 1985 - Springer
Thirty-seven clinical isolates of coxsackievirus (CV) serotypes B-1, B-3, B-4, and B-5 were
inoculated into male SJL mice. Twelve strains resulted in minor abnormalities of glucose …
inoculated into male SJL mice. Twelve strains resulted in minor abnormalities of glucose …
Predisposing effect of anti-beta cell autoimmune process in NOD mice on the induction of diabetes by environmental insults
SH Ihm, KU Lee, RG McArthur, JW Yoon - Diabetologia, 1990 - Springer
Summary In NOD mice, 50–70% of females and 10–20% of males develop diabetes,
although almost all the animals show insulitis. To see if environmental insults could induce …
although almost all the animals show insulitis. To see if environmental insults could induce …
[PDF][PDF] L'immunologia del diabete mellito
P Pozzilli, R Buzzetti, E Procaccini, E Signore - medicalsystems.it
L'immunologia ha rappresentato in quest'ultimo periodo la chiave interpretativa di molti
fenomeni patogenetici ritenuti altrimenti oscuri o difficilmente comprensibili (1). Infatti, se …
fenomeni patogenetici ritenuti altrimenti oscuri o difficilmente comprensibili (1). Infatti, se …
Herpes virus infections in human pancreas islets and animal models
T Kurata, T Sata, T Iwasaki, T Onodera… - Virus Infections and …, 1987 - Springer
The pancreatic tissue from 131 human cases with fatal herpes infections were
viropathoiogically examined for islet lesions. Diagnoses of all cases were confirmed by virus …
viropathoiogically examined for islet lesions. Diagnoses of all cases were confirmed by virus …
A case for immune response genes?
G Reeves - Immunology Today, 1983 - Elsevier
Diabetes is not a single disease. Some patients develop insulin deficiency fairly rapidly and
these are usually young, have lymphocytic infiltration of their pancreatic islets, possess …
these are usually young, have lymphocytic infiltration of their pancreatic islets, possess …
Autoimmune Mechanisms in The Etiology of Type I Diabetes
P Santamaria, M Nagata, JW Yoon - Clinical Pediatric Endocrinology, 1994 - jstage.jst.go.jp
Considerable evidence has been accumulated showing that most cases of
insulindependent diabetes mellitus (IDDM) are a consequence of progressive beta cell …
insulindependent diabetes mellitus (IDDM) are a consequence of progressive beta cell …
Autoantibody to α-Amylase in the Non-obese Diabetic Mouse
K MURAKAMI, Y SUZUKI, M NAKAMURA… - The Showa University …, 1996 - jstage.jst.go.jp
The non-obese diabetic (NOD) mouse has been developed as an animal model of insulin-
dependent diabetes mellitus (IDDM). The islet cell autoantibody and autoantibodies to …
dependent diabetes mellitus (IDDM). The islet cell autoantibody and autoantibodies to …