[HTML][HTML] A neuroradiologist's guide to arterial spin labeling MRI in clinical practice

M Grade, JA Hernandez Tamames, FB Pizzini… - Neuroradiology, 2015 - Springer
Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

Brain imaging in comatose survivors of cardiac arrest: pathophysiological correlates and prognostic properties

HM Keijzer, CWE Hoedemaekers, FJA Meijer… - Resuscitation, 2018 - Elsevier
Introduction Hypoxic-ischemic brain injury is the main cause of death and disability of
comatose patients after cardiac arrest. Early and reliable prognostication is challenging …

[HTML][HTML] ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

HJMM Mutsaerts, J Petr, P Groot, P Vandemaele… - Neuroimage, 2020 - Elsevier
Arterial spin labeling (ASL) has undergone significant development since its inception, with
a focus on improving standardization and reproducibility of its acquisition and quantification …

[HTML][HTML] Ultra-long-TE arterial spin labeling reveals rapid and brain-wide blood-to-CSF water transport in humans

L Petitclerc, L Hirschler, JA Wells, DL Thomas… - Neuroimage, 2021 - Elsevier
The study of brain clearance mechanisms is an active area of research. While we know that
the cerebrospinal fluid (CSF) plays a central role in one of the main existing clearance …

[HTML][HTML] Cerebrovascular reactivity measurements using simultaneous 15O-water PET and ASL MRI: Impacts of arterial transit time, labeling efficiency, and hematocrit

MY Zhao, AP Fan, DYT Chen, MJ Sokolska, J Guo… - Neuroimage, 2021 - Elsevier
Cerebrovascular reactivity (CVR) reflects the capacity of the brain to meet changing
physiological demands and can predict the risk of cerebrovascular diseases. CVR can be …

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

HJMM Mutsaerts, SS Mirza, J Petr, DL Thomas… - Brain, 2019 - academic.oup.com
Genetic forms of frontotemporal dementia are most commonly due to mutations in three
genes, C9orf72, GRN or MAPT, with presymptomatic carriers from families representing …

[HTML][HTML] Quantitative water permeability mapping of blood-brain-barrier dysfunction in aging

JN Ford, Q Zhang, EM Sweeney, AE Merkler… - Frontiers in Aging …, 2022 - frontiersin.org
Blood-brain-barrier (BBB) dysfunction is a hallmark of aging and aging-related disorders,
including cerebral small vessel disease and Alzheimer's disease. An emerging biomarker of …

Multi-vendor reliability of arterial spin labeling perfusion MRI using a near-identical sequence: implications for multi-center studies

HJMM Mutsaerts, MJ Van Osch, FO Zelaya, DJJ Wang… - Neuroimage, 2015 - Elsevier
Introduction A main obstacle that impedes standardized clinical and research applications of
arterial spin labeling (ASL), is the substantial differences between the commercial …

[HTML][HTML] Robust multi-TE ASL-based blood–brain barrier integrity measurements

A Mahroo, MA Buck, J Huber, NJ Breutigam… - Frontiers in …, 2021 - frontiersin.org
Multiple echo-time arterial spin labelling (multi-TE ASL) offers estimation of blood–tissue
exchange dynamics by probing the T2 relaxation of the labelled spins. In this study, we …

[HTML][HTML] Secondary prevention of Alzheimer's dementia: neuroimaging contributions

M Ten Kate, S Ingala, AJ Schwarz, NC Fox… - Alzheimer's research & …, 2018 - Springer
Abstract Background In Alzheimer's disease (AD), pathological changes may arise up to 20
years before the onset of dementia. This pre-dementia window provides a unique …