Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery.
However, cancers often develop resistance against drugs, leading to failure of treatment and …

Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

Cancer is one of the leading causes of death in the world. Chemotherapy is presented as an
option for treatment of this disease, however, low specificity, high resistance rates, toxicity …

Recent strategies for the treatment of cancer, other than just tumor cell killing have been
under intensive development, such as anti-angiogenic therapeutic approach. Angiogenesis …

Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …

The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or
protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally …

Abstract Ribonucleotide reductase M2 (RRM2) is a small subunit in ribonucleotide
reductases, which participate in nucleotide metabolism and catalyze the conversion of …

Acquired drug resistance represents a major clinical problem and one of the biggest
limitations of chemotherapeutic regimens in colorectal cancer. Combination regimens using …

Natural product compounds have lately attracted interest in the scientific community as a
possible treatment for gastrointestinal (GI) cancer, due to their anti-inflammatory and …

Nutrigenomics effects have an important role in the manipulation of dietary components for
human benefit, particularly in cancer prevention or treatment. The impact of dietary …