Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

Irisin is a myokine that leads to increased energy expenditure by stimulating the'browning'of
white adipose tissue. In the first description of this hormone, increased levels of circulating …

White adipose tissue (WAT) is an endocrine organ highly integrated in homeostasis and
capable of establishing ways of communicating and influencing multiple metabolic …

Rationale: The newly discovered myokine irisin has been proposed to affect obesity and
metabolism by promoting browning of white adipose tissue. However, clinical and functional …

Objective We determined detailed time-course changes in the irisin response to acute
exercise using different exercise modes. Methods In experiment 1, seven healthy males …

Abstract Purpose of Review The purpose of this review is to summarize our current
understanding of the association between childhood obesity and cancer risk later in life …

The prevalence of obesity continues to rise worldwide despite evidence-based public health
recommendations. The promise to adopt a healthy lifestyle is increasingly important for …

A biological activity of myokine irisin, has been intensively investigated in the context of a
browning process occurring in white adipose tissue, but its role as a modulator of immune …

Irisin is a novel myokine and adipokine that has gained much attention recently due to its
mechanisms of action. Irisin is secreted following proteolytic cleavage of its precursor …

Physical exercise may activate a number of important biochemical processes in the human
body. The aim of this systematic review and meta-analysis was to identify the long-term …