Neuropeptide Y (NPY) is widely distributed in the human body and contributes to a vast
number of physiological processes. Since its discovery, NPY has been implicated in …

One of the challenges of cancer is its heterogeneity and rapid capacity to adapt.
Notwithstanding significant progress in the last decades in genomics and precision …

Background Altered networks of gene regulation underlie many complex conditions,
including cancer. Inferring gene regulatory networks from high-throughput microarray …

The notion that tumors lack innervation was proposed several years ago. However, nerve
fibers are irregulatedly found in some tumor tissues. Their terminals interaction with cancer …

Abstract NPY, PYY and PP constitute the so‐called NPY hormone family, which exert its
biological functions in humans through YRs (Y1, Y2, Y4 and Y5). Systematic modulation of …

Neuropeptides are small regulatory molecules found throughout the body, most notably in
the nervous, cardiovascular, and gastrointestinal systems. They serve as neurotransmitters …

Oral squamous cell carcinoma (OSCC) constitutes> 90% of oral cancers and is the sixth
most common malignancy among males worldwide and the fourth leading cause of death …

Neuropeptides are autocrine and paracrine signalling factors and mainly bind to G protein-
coupled receptors (GPCRs) to trigger intracellular secondary messenger release including …

The nervous system has been recently shown to exert impact on gastric cancer directly and
indirectly. Gastric cancer cells invade nerve fibers to induce outgrowth and branching of …

Stress has long been thought of to be associated with increased risk of cancer. Chronic
stress is associated with elevated levels of sympathetic neurotransmitter (norepinephrine …