Ketocholesterol (7KC) is a toxic oxysterol that is associated with many diseases and
disabilities of aging, as well as several orphan diseases. 7KC is the most common product of …

Astrocytes are the main support cells of the central nervous system. They also participate in
neuroimmune reactions. In response to pathological and immune stimuli, astrocytes …

Oxidative and inflammatory signaling pathways have been identified as important targets for
mitigating hypoxic stress-induced neurological complications. Thus, the effects of …

Abstract The new coronavirus (COVID-19) has emerged now in the world as a pandemic.
The SARS-CoV-2 infection causes variant common symptoms, such as dry cough, tiredness …

Chronic hypobaric hypoxia in high‐altitude areas is closely related to the occurrence of
many neurological diseases. Among these diseases, epilepsy is a common disease of the …

During the past decade,“membrane lipid therapy”, which involves the regulation of the
structure and function of tumor cell plasma membranes, has emerged as a new strategy for …

This study aimed to investigate the potential anti-aging mechanisms of Agrocybe
cylindracea crude polysaccharides (APS), when used synergistically with Lactobacillus …

Inadequate oxygen availability at high altitude leads to oxidative stress, resulting in
hippocampal neurodegeneration and memory impairment. In our previous study, we found …

Cholinergic basal forebrain (cBF) neurons are particularly vulnerable to degeneration
following trauma and in neurodegenerative conditions. One reason for this is their …

The high-altitude environment is characterized by hypobaric hypoxia, low temperatures, low
humidity, and high radiation, which is a natural challenge for lowland residents entering …