Major depressive disorder (MDD) and bipolar disorder (BD) lack robust biomarkers useful
for screening purposes in a clinical setting. A systematic review of the literature was …

Neurometabolic diseases (NMDs) are typically caused by genetic abnormalities affecting
enzyme functions, which in turn interfere with normal development and activity of the …

Inborn errors of metabolism (IEMs) may present in adolescence or adulthood as a
psychiatric disorder. In some instances, an IEM is suspected because of informative family …

Objective Nonketotic hyperglycinemia is a neurometabolic disorder characterized by
intellectual disability, seizures, and spasticity. Patients with attenuated nonketotic …

Nonketotic hyperglycinemia (NKH) is an inborn error of metabolism characterized by
accumulation of glycine in body fluids and various neurological symptoms. NKH is caused …

Clinical symptoms in atypical nonketotic hyperglycinemia (NKH) are heterogeneous, in
sharp contrast to uniform severe neurological symptoms in the classical NKH. A review of …

Patients with severe nonketotic hyperglycinemia (NKH) have absent psychomotor
development and intractable epilepsy, whereas attenuated patients have variable …

The pediatric neurotransmitter disorders represent an enlarging group of neurological
syndromes characterized by abnormalities of neurotransmitter synthesis and breakdown …

Inherited disorders of neurotransmitters are a group of neurometabolic syndromes
attributable to a primary disturbance of neurotransmitter metabolism or transport. This is an …

Background: Non-ketotic hyperglycinaemia (NKH) is an inborn error of metabolism
characterised by accumulation of glycine in body fluids and various neurological symptoms …