Executive summary Around the world, populations are ageing at a faster pace than in the
past and this demographic transition will have effects on all aspects of societies. In May …

Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

Background Falls in older people have become a major public health concern worldwide,
but a comprehensive assessment of the burden of falls for older people in mainland China …

Background Previous studies indicated that obesity would accelerate frailty progression.
However, obesity is heterogeneous by different metabolic status. The associations of …

Abstract Background and Aims Previous studies found that frailty was an important risk factor
for cardiovascular disease (CVD). However, previous studies only focused on baseline …

Background Rheumatoid arthritis is a chronic autoimmune disorder that affects life
expectancy. Accelerated biological ageing is thought to be a major risk factor for age-related …

Background Social participation (SP) may be an effective measure for decreasing frailty
risks. This study investigated whether frequency and type of SP is associated with …

Background Little is known about the effects of maintaining healthy sleep patterns on frailty
transitions. Methods Based on 23,847 Chinese adults aged 30–79 in a prospective cohort …

The prompt identification of frailty in primary care is the first step to offer personalized care to
older individuals. We aimed to detect and quantify frailty among primary care older patients …

Background Frailty is a public health problem for ageing society, however, evidence is
lacking regarding its impact on intestinal functions. We aimed to examine prospective …