Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …

Macroautophagy/autophagy occurs at basal levels in all eukaryotic cells and plays an
important role in maintaining bio-energetic homeostasis through the control of molecule …

Mesenchymal stromal cells (MSCs) as a pharmaceutical for ailments characterized by
pathogenic autoimmune, alloimmune and inflammatory processes now cover the spectrum …

The mechanisms underlying immunomodulatory ability of mesenchymal stromal cells
(MSCs) remain unknown. Recently, studies suggested that the immunomodulatory activity of …

Assays that can characterize MSC immune potency need to be identified for use in
advanced clinical trials. MSCs possess a number of putative regenerative and …

We have previously demonstrated that cryopreservation and thawing lead to altered
Mesenchymal stromal cells (MSC) functionalities. Here, we further analyzed MSC's fitness …

Perianal fistulizing Crohn's disease (PFCD) is associated with significant morbidity and
might negatively impact the quality of life of CD patients. In the last two decades, the …

Rapid progress is occurring in understanding the mechanisms underlying mesenchymal
stromal cell (MSC)-based cell therapies (MSCT). However, the results of clinical trials, while …

Mesenchymal stromal cells (MSC) are a heterogeneous cell population with self-renewal
and the ability to differentiate into different lineages. The novel regulatory role of MSC in …

Background Mesenchymal stromal cells ability to reset immune functionalities may be useful
in Crohn's disease. Aim To perform a first‐in‐human phase 1 safety clinical trial of …