The severe Duchenne and milder Becker muscular dystrophy are both caused by mutations
in the DMD gene. This gene codes for dystrophin, a protein important for maintaining the …

Duchenne and Becker muscular dystrophies are caused by defects of the dystrophin gene.
Expression of this large X-linked gene is under elaborate transcriptional and splicing control …

BACKGROUND X-linked cardiomyopathy (XLCM) is a rapidly progressive primary
myocardial disorder presenting in teenage males as congestive heart failure. Manifesting …

Becker muscular dystrophy (BMD) often results from in-frame mutations of the dystrophin
gene that allow production of an altered but partially functional protein. To address potential …

Deletions and point mutations in the gene encoding the cytoskeletal protein dystrophin and
its isoforms cause either the severe progressive myopathy Duchenne muscular dystrophy …

The primary cause of Duchenne muscular dystrophy (DMD) is a mutation in the dystrophin
gene leading to the absence of the corresponding RNA transcript and protein. Absence of …

It appears that no organism is immune to the effects of nonsense codons on mRNA
abundance. The study of how nonsense codons alter RNA metabolism is still at an early …

Dystrophinopathies result from mutations of the DMD gene that primarily affect skeletal
muscle but also affect heart, brain, and smooth muscle. Advances in the genetic analysis of …

Hypobetalipoproteinemia is an autosomal codominant disorder characterized by decreased
or absent plasma concentrations of the apolipoprotein (apo) B-containing lipoproteins …

Genome‐wide gene expression profiling of skeletal muscle from Duchenne muscular
dystrophy (DMD) patients has been used to describe muscle tissue alterations in DMD …