Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in …

NL Albert, M Weller, B Suchorska, N Galldiks… - Neuro …, 2016 - academic.oup.com
This guideline provides recommendations for the use of PET imaging in gliomas. The review
examines established clinical benefit in glioma patients of PET using glucose (18F-FDG) …

Current standards of care in glioblastoma therapy

C Fernandes, A Costa, L Osório, RC Lago… - Exon …, 2017 - exonpublications.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II …

N Butowski, H Colman, JF De Groot, AM Omuro… - Neuro …, 2015 - academic.oup.com
Background The colony stimulating factor 1 receptor (CSF1R) ligands, CSF1 and interleukin-
34, and the KIT ligand, stem cell factor, are expressed in glioblastoma (GB). Microglia …

Contribution of PET imaging to radiotherapy planning and monitoring in glioma patients-a report of the PET/RANO group

N Galldiks, M Niyazi, AL Grosu, M Kocher… - Neuro …, 2021 - academic.oup.com
The management of patients with glioma usually requires multimodality treatment including
surgery, radiotherapy, and systemic therapy. Accurate neuroimaging plays a central role for …

Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma

Z Chen, N Soni, G Pinero, B Giotti, DJ Eddins… - Nature …, 2023 - nature.com
Myeloid cells comprise the majority of immune cells in tumors, contributing to tumor growth
and therapeutic resistance. Incomplete understanding of myeloid cells response to tumor …

Molecular biomarkers in glioblastoma: A systematic review and meta-analysis

H Sareen, Y Ma, TM Becker, TL Roberts… - International journal of …, 2022 - mdpi.com
Background: Glioblastoma (GBM) is a highly aggressive cancer with poor prognosis that
needs better treatment modalities. Moreover, there is a lack of reliable biomarkers to predict …

[HTML][HTML] Toxicity of concurrent stereotactic radiotherapy and targeted therapy or immunotherapy: a systematic review

SGC Kroeze, C Fritz, M Hoyer, SS Lo, U Ricardi… - Cancer treatment …, 2017 - Elsevier
Background and purpose Both stereotactic radiotherapy (SRT) and immune-or targeted
therapy play an increasingly important role in personalized treatment of metastatic disease …

[HTML][HTML] Glioblastoma treatment modalities besides surgery

H Zhang, R Wang, Y Yu, J Liu, T Luo, F Fan - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS
tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy …

Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

I Kaffes, F Szulzewsky, Z Chen, CJ Herting… - …, 2019 - Taylor & Francis
Glioblastoma (GBM) is the most aggressive malignant primary brain tumor in adults, with a
median survival of 14.6 months. Recent efforts have focused on identifying clinically relevant …

The radiosurgery fractionation quandary: single fraction or hypofractionation?

JP Kirkpatrick, SG Soltys, SS Lo, K Beal… - Neuro …, 2017 - academic.oup.com
Stereotactic radiosurgery (SRS), typically administered in a single session, is widely
employed to safely, efficiently, and effectively treat small intracranial lesions. However, for …