Semaphorins and their receptors: from axonal guidance to atherosclerosis
S Hu, L Zhu - Frontiers in physiology, 2018 - frontiersin.org
Semaphorins are a large family of secreted, transmembrane, or GPI-anchored proteins
initially identified as axon guidance cues signaling through their receptors, neuropilins, and …
initially identified as axon guidance cues signaling through their receptors, neuropilins, and …
[HTML][HTML] miR-19a/b and miR-20a promote wound healing by regulating the inflammatory response of keratinocytes
Persistent and impaired inflammation impedes tissue healing and is a characteristic of
chronic wounds. A better understanding of the mechanisms controlling wound inflammation …
chronic wounds. A better understanding of the mechanisms controlling wound inflammation …
SEMA7a primes integrin α5β1 engagement instructing fibroblast mechanotransduction, phenotype and transcriptional programming
Integrins are cellular receptors that bind the extracellular matrix (ECM) and facilitate the
transduction of biochemical and biophysical microenvironment cues into cellular responses …
transduction of biochemical and biophysical microenvironment cues into cellular responses …
Vascular semaphorin 7A upregulation by disturbed flow promotes atherosclerosis through endothelial β1 integrin
S Hu, Y Liu, T You, J Heath, L Xu, X Zheng… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Accumulating evidence suggests a role of semaphorins in vascular homeostasis.
Here, we investigate the role of Sema7A (semaphorin 7A) in atherosclerosis and its …
Here, we investigate the role of Sema7A (semaphorin 7A) in atherosclerosis and its …
Macphatics and PoEMs in postpartum mammary development and tumor progression
Postpartum mammary gland involution is a mammalian tissue remodeling event that occurs
after pregnancy and lactation to return the gland to the pre-pregnant state. This event is …
after pregnancy and lactation to return the gland to the pre-pregnant state. This event is …
Comparison and combination of blood DNA methylation at smoking‐associated genes and at lung cancer‐related genes in prediction of lung cancer mortality
Y Zhang, LP Breitling, Y Balavarca… - … journal of cancer, 2016 - Wiley Online Library
Epigenome‐wide association studies have established methylation patterns related to
smoking, the major risk factor of lung cancer (LC), which are distinct from methylation …
smoking, the major risk factor of lung cancer (LC), which are distinct from methylation …
[HTML][HTML] Sema7A protects against high-fat diet-induced obesity and hepatic steatosis by regulating adipo/lipogenesis
Q Lu, Z Liu, L Zhao, L Xu, C Liu, L Li, Y Cao, F Li… - Molecular …, 2023 - Elsevier
Objective Obesity and related diseases are becoming a growing risk for public health
around the world due to the westernized lifestyle. Sema7A, an axonal guidance molecule …
around the world due to the westernized lifestyle. Sema7A, an axonal guidance molecule …
Suppression of tumor-derived Semaphorin 7A and genetic ablation of host-derived Semaphorin 7A impairs tumor progression in a murine model of advanced breast …
R Garcia-Areas, S Libreros… - International …, 2017 - spandidos-publications.com
Solid tumors can generate a plethora of neurogenesis-related molecules that enhance their
growth and metastasis. Among them, we have identified axonal guidance molecule …
growth and metastasis. Among them, we have identified axonal guidance molecule …
A Comprehensive Prognostic Analysis of Tumor-Related Blood Group Antigens in Pan-Cancers Suggests That SEMA7A as a Novel Biomarker in Kidney Renal Clear …
Y Wang, C Li, X Qi, Y Yao, L Zhang, G Zhang… - International Journal of …, 2022 - mdpi.com
Blood group antigen is a class of heritable antigenic substances present on the erythrocyte
membrane. However, the role of blood group antigens in cancer prognosis is still largely …
membrane. However, the role of blood group antigens in cancer prognosis is still largely …
Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer
Breast cancer is a global health threat and cases diagnosed in women during the years after
childbirth, or postpartum breast cancers (PPBCs), have high risk for metastasis. In preclinical …
childbirth, or postpartum breast cancers (PPBCs), have high risk for metastasis. In preclinical …