Angiotensin-converting enzyme (ACE) 2 is a homolog to the carboxypeptidase ACE, which
generates angiotensin II, the main active peptide of renin–angiotensin system (RAS). After …

In recent years, the focus of interest on the role of the renin-angiotensin system (RAS) in the
pathophysiology of hypertension and organ injury has changed to a major emphasis on the …

Angiotensin II content in the kidney is much higher than in the plasma, and it increases more
in kidney diseases through an uncertain mechanism. Because the kidney abundantly …

BACKGROUND: Angiotensin-converting enzyme (ACE) 2 (ACE2) is expressed mainly in the
heart and kidney and forms angiotensin-1-7 from angiotensin II. ACE2 might act in a …

Abstract Coronavirus disease 2019 (COVID-19) is a declared pandemic that is spreading all
over the world at a dreadfully fast rate. Severe acute respiratory syndrome coronavirus-2 …

Angiotensin-converting enzyme 2 (ACE2) is a monocarboxypeptidase that degrades
angiotensin II with high efficiency leading to the formation of angiotensin-(1–7). ACE2 within …

Excessive proteinuria leads to renal dysfunction and damage. Ganoderma lucidum
polysaccharide peptide (GL-PP) and Ganoderma lucidum polysaccharide peptide 2 (GL …

Renal toxicity constitutes a dose-limiting side effect of anticancer therapies targeting
vascular endothelial growth factor (VEGF). In order to study this further, we followed up 29 …

Recent studies emphasize the role of chronic hypoxia in the kidney as a final common
pathway to end-stage renal failure (ESRD). Hypoxia of tubular cells leads to apoptosis or …

Cancer patients have an incidence of about 60% kidney disease development and are at
elevated risk of acute renal damage. Kidney disease in these patients is frequently …