Signaling, metabolism, and cancer: An important relationship for therapeutic intervention
In cancerous cells, significant changes occur in the activity of signaling pathways affecting a
wide range of cellular activities ranging from growth and proliferation to apoptosis …
wide range of cellular activities ranging from growth and proliferation to apoptosis …
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect
H Liu, X Zhang, P Shi, J Yuan, Q Jia, C Pi… - Journal of …, 2023 - Springer
Depression is a common mental illness, which is related to monoamine neurotransmitters
and the dysfunction of the cholinergic, immune, glutamatergic, and neuroendocrine systems …
and the dysfunction of the cholinergic, immune, glutamatergic, and neuroendocrine systems …
Hyperoside induces breast cancer cells apoptosis via ROS-mediated NF-κB signaling pathway
J Qiu, T Zhang, X Zhu, C Yang, Y Wang… - International Journal of …, 2019 - mdpi.com
Hyperoside (quercetin 3-o-β-d-galactopyranoside) is one of the flavonoid glycosides with
anti-inflammatory, antidepressant, and anti-cancer effects. But it remains unknown whether it …
anti-inflammatory, antidepressant, and anti-cancer effects. But it remains unknown whether it …
Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and …
J Zhao, L Huang, C Sun, D Zhao, H Tang - Food chemistry, 2020 - Elsevier
In this study, some flavonoids were screened as potent xanthine oxidase (XO) inhibitors in
vitro. Flavonoid 9 was demonstrated to exhibit the inhibitory activity through a ping-pong …
vitro. Flavonoid 9 was demonstrated to exhibit the inhibitory activity through a ping-pong …
Iron Oxide and Silicon Nanoparticles Modulate Mineral Nutrient Homeostasis and Metabolism in Cadmium-Stressed Phaseolus vulgaris
The application of nanoparticles (NPs) has been proved as an efficient and promising
technique for mitigating a wide range of stressors in plants. The present study elucidates the …
technique for mitigating a wide range of stressors in plants. The present study elucidates the …
[HTML][HTML] Klebsiella pneumoniae producing bacterial toxin colibactin as a risk of colorectal cancer development-A systematic review
N Strakova, K Korena, R Karpiskova - Toxicon, 2021 - Elsevier
Microbiota can significantly contribute to colorectal cancer initiation and development. It was
described that E. coli harbouring polyketide synthase (pks) genes can synthetize bacterial …
described that E. coli harbouring polyketide synthase (pks) genes can synthetize bacterial …
Tangeretin: A mechanistic review of its pharmacological and therapeutic effects
M Ashrafizadeh, Z Ahmadi… - Journal of basic and …, 2020 - degruyter.com
To date, a large number of synthetic drugs have been developed for the treatment and
prevention of different disorders, such as neurodegenerative diseases, diabetes mellitus …
prevention of different disorders, such as neurodegenerative diseases, diabetes mellitus …
Function and mechanisms of microRNA‑20a in colorectal cancer
Z Xiao, S Chen, S Feng, Y Li, J Zou… - Experimental and …, 2020 - spandidos-publications.com
Colorectal cancer (CRC) is the third most common malignancy and the second leading
cause of cancer‑associated mortality worldwide. CRC currently has no specific biomarkers …
cause of cancer‑associated mortality worldwide. CRC currently has no specific biomarkers …
Elephantopinolide AP, germacrane-type sesquiterpene lactones from Elephantopus scaber induce apoptosis, autophagy and G2/M phase arrest in hepatocellular …
M Bai, JJ Chen, W Xu, SH Dong, QB Liu, B Lin… - European Journal of …, 2020 - Elsevier
Chromatographic purification of Elephantopus scaber led to 16 new germacrane-type
sesquiterpene lactones (1–16), named elephantopinolide AP, along with a known analogue …
sesquiterpene lactones (1–16), named elephantopinolide AP, along with a known analogue …
[HTML][HTML] Urinary volatile organic compounds for colorectal cancer screening: A systematic review and meta-analysis
ELSA van Liere, LJ van Dijk, S Bosch… - European Journal of …, 2023 - Elsevier
Background The faecal immunochemical test (FIT) suffers from suboptimal performance and
participation in colorectal cancer (CRC) screening. Urinary volatile organic compounds …
participation in colorectal cancer (CRC) screening. Urinary volatile organic compounds …