Intervertebral disc degeneration (IDD) and associated conditions are an important problem
in modern medicine. The onset of IDD may be in childhood and adolescence in patients with …

The major goal of animal breeding is the genetic enhancement of economic traits. The
CRISPR/Cas system, which includes nuclease-mediated and base editor mediated genome …

Simple Summary One of the traits considered in livestock production is the gain of muscle
mass, which is one of the factors responsible for governing the growth of skeletal muscles …

The limited knowledge of genomic noncoding and regulatory regions has restricted our
ability to decipher the genetic mechanisms underlying complex traits in pigs. In this study …

Botulinum toxin-A (BTX) administration into muscle is an established treatment for conditions
with excessive muscle contraction. However, botulinum therapy has short-term …

Sepsis‐induced muscle atrophy often increases morbidity and mortality in intensive care unit
(ICU) patients, yet neither therapeutic target nor optimal animal model is available for this …

African rainforests support exceptionally high biodiversity and host the world's largest
number of active hunter-gatherers [1–3]. The genetic history of African rainforest hunter …

Background Inflammatory bowel disease (IBD) has complex genetic and environmental
aspects, and free fatty acid receptors (FFARs) may bridge genetic and dietary aspects …

Insulin-like growth factor 2 (IGF2) plays an important role in the development of the foetus
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …

ZC3H11A (zinc finger CCCH domain–containing protein 11A) is a stress-induced mRNA-
binding protein required for efficient growth of nuclear-replicating viruses. The cellular …