Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies

DM Wingerchuk, JL Carter - Mayo Clinic Proceedings, 2014 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating central nervous system
disease that typically strikes young adults, especially women. The pathobiology of MS …

[HTML][HTML] Disease-modifying therapies and infectious risks in multiple sclerosis

A Winkelmann, M Loebermann, EC Reisinger… - Nature Reviews …, 2016 - nature.com
Immunomodulatory and immunosuppressive treatments for multiple sclerosis (MS) are
associated with an increased risk of infection, which makes treatment of this condition …

[HTML][HTML] Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation

JA Snowden, R Saccardi, M Allez… - Bone marrow …, 2012 - nature.com
In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune
diseases (ADs) were published, while an international coordinated clinical programme was …

Disease modifying therapies for relapsing multiple sclerosis

DM Wingerchuk, BG Weinshenker - Bmj, 2016 - bmj.com
Multiple sclerosis (MS) is a common, disabling, putatively autoimmune neurological disease
with worldwide distribution. It typically begins as a relapsing disorder that later evolves to a …

The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis

G Mallucci, L Peruzzotti-Jametti, JD Bernstock… - Progress in …, 2015 - Elsevier
Multiple sclerosis is one of the most common causes of chronic neurological disability
beginning in early to middle adult life. Multiple sclerosis is idiopathic in nature, yet …

Consensus statement: evaluation of new and existing therapeutics for pediatric multiple sclerosis

T Chitnis, S Tenembaum, B Banwell… - Multiple Sclerosis …, 2012 - journals.sagepub.com
New therapies are being evaluated by clinical trials and, if efficacious, introduced for the
treatment of adult MS. The role of these new and existing agents in the management of …

Mitoxantrone for multiple sclerosis

FM Boneschi, L Vacchi, M Rovaris… - Cochrane Database …, 2013 - cochranelibrary.com
Mitoxantrone for multiple sclerosis - Martinelli Boneschi, F - 2013 | Cochrane Library Skip to
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Aggressive multiple sclerosis: proposed definition and treatment algorithm

CA Rush, HJ MacLean, MS Freedman - Nature Reviews Neurology, 2015 - nature.com
Multiple sclerosis (MS) is a CNS disorder characterized by inflammation, demyelination and
neurodegeneration, and is the most common cause of acquired nontraumatic neurological …

[HTML][HTML] Multiple sclerosis: New insights and trends

KMM Koriem - Asian Pacific Journal of Tropical Biomedicine, 2016 - Elsevier
Multiple sclerosis (MS) is the most famous autoimmune disease attacking the central
nervous system. It attacks people from age 20–50 years old and the females' attacks double …

Mycophenolate mofetil in the treatment of neuromyelitis optica spectrum disorder

SY Huh, SH Kim, JW Hyun, AR Joung, MS Park… - JAMA …, 2014 - jamanetwork.com
Importance Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune
inflammatory disorder of the central nervous system. Recently, various immunosuppressant …