Isoflavones: estrogenic activity, biological effect and bioavailability

DC Vitale, C Piazza, B Melilli, F Drago… - European journal of drug …, 2013 - Springer
Isoflavones are phytoestrogens with potent estrogenic activity; genistein, daidzein and
glycitein are the most active isoflavones found in soy beans. Phytoestrogens have similarity …

[HTML][HTML] Estrogen, angiogenesis, immunity and cell metabolism: solving the puzzle

A Trenti, S Tedesco, C Boscaro, L Trevisi… - International journal of …, 2018 - mdpi.com
Estrogen plays an important role in the regulation of cardiovascular physiology and the
immune system by inducing direct effects on multiple cell types including immune and …

Obesity and weight management in the elderly

TS Han, A Tajar, MEJ Lean - British medical bulletin, 2011 - academic.oup.com
Our population is ageing, and obesity is increasing in the elderly bringing massive and
rapidly changing burdens of ill health related to increased body weights and fat as well as …

Sex differences in risk factors for vascular contributions to cognitive impairment & dementia

OJ Gannon, LS Robison, AJ Custozzo… - Neurochemistry …, 2019 - Elsevier
Vascular contributions to cognitive impairment and dementia (VCID) is the second most
common cause of dementia. While males overall appear to be at a slightly higher risk for …

Estrogen signaling in metabolic inflammation

R Monteiro, D Teixeira, C Calhau - Mediators of inflammation, 2014 - Wiley Online Library
There is extensive evidence supporting the interference of inflammatory activation with
metabolism. Obesity, mainly visceral obesity, is associated with a low‐grade inflammatory …

Contributions of sex to cerebrovascular function and pathology

LS Robison, OJ Gannon, AE Salinero, KL Zuloaga - Brain research, 2019 - Elsevier
Sex differences exist in how cerebral blood vessels function under both physiological and
pathological conditions, contributing to observed sex differences in risk and outcomes of …

Genistein in the metabolic syndrome: results of a randomized clinical trial

F Squadrito, H Marini, A Bitto, D Altavilla… - The Journal of …, 2013 - academic.oup.com
Context: This study was performed to evaluate the effects of genistein on metabolic and
cardiovascular risk factors in Caucasian postmenopausal subjects with metabolic syndrome …

[PDF][PDF] Obesity in the elderly: more complicated than you think

DC Do Cetin, G Nasr - Cleveland clinic Journal of medicine, 2014 - scholar.archive.org
The number of obese older adults is on the rise, although we lack a proper definition of
obesity in this age group. The ambiguity is primarily related to sarcopenia, the progressive …

Effectiveness of genistein supplementation on metabolic factors and antioxidant status in postmenopausal women with type 2 diabetes mellitus

H Braxas, M Rafraf, SK Hasanabad… - Canadian journal of …, 2019 - Elsevier
Objectives The risk of type 2 diabetes mellitus (T2DM) increases in women after
menopause. Genistein is known to modulate metabolic pathways. The aim of this study was …

[HTML][HTML] Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α

S Della Torre, V Benedusi, G Pepe, C Meda… - Nature …, 2021 - nature.com
In female mammals, the cessation of ovarian functions is associated with significant
metabolic alterations, weight gain, and increased susceptibility to a number of pathologies …