As a research hotspot, the development of magnetic resonance imaging (MRI) contrast
agents has attracted great attention over the past decades for improving the accuracy of …

Cancer is a disease that has resulted in millions of deaths worldwide. The current
conventional therapies utilized for the treatment of cancer have detrimental side effects. This …

There are several endogenous molecules that can trigger migraine attacks when
administered to humans. Notably, calcitonin gene-related peptide (CGRP) has been …

The iron oxide nanoparticles (IONPs), possessing both magnetic behavior and
semiconductor property, have been extensively used in multifunctional biomedical fields due …

Background Pain is generally concomitant with an inflammatory reaction at the site where
the nociceptive fibers are activated. Rodent studies suggest that a sterile meningeal …

Migraine is the most common neurological disorder in the world, affecting 12% of the
population. Migraine involves the central nervous system, trigeminal nerves and meninges …

Various explanations for the pathophysiology of migraines have been proposed; however,
none of these provide a complete explanation. The author critically reviews previous …

Accumulating evidence suggests that inflammation is not limited to archetypal inflammatory
diseases such as multiple sclerosis, but instead represents an intrinsic feature of many …

Migraine is a prevalent and debilitating neurologic disorder. Advancements in
understanding the underlying pathophysiological mechanisms are spearheading the effort …

Among painful disorders, migraine is distinguishable by its chronic pathology and episodic
clinical manifestation. Only a small percentage of patients with migraine progress to a …