As membrane-associated master regulators of cytoskeletal remodeling, Rho GTPases
coordinate a wide range of biological processes such as cell adhesion, motility, and polarity …

Metastatic dissemination represents the final stage of tumor progression as well as the
principal cause of cancer‐associated deaths. Calpains are a conserved family of calcium …

Epithelial-to-mesenchymal transition (EMT) underlies immunosuppression, drug resistance,
and metastasis in epithelial malignancies. However, the way in which EMT orchestrates …

Tunneling nanotubes (TNTs) are actin-enriched membranous channels enabling cells to
communicate over long distances. TNT-like structures form between various cell types and …

Abstract Phosphatidylethanolamine-binding protein 1 (PEBP1), a small 21 kDa protein, is
implicated in several key processes of the living cell. The deregulation of PEBP1, especially …

In addition to the classical pathway of secretion, some transmembrane proteins reach the
plasma membrane through alternative routes. Several proteins transit through endosomes …

The small GTPases of the Rho family regulate many aspects of actin dynamics, but are
functionally connected to many other cellular processes. Rac1, a member of this family …

Streptococcus agalactiae (S. agalactiae) is a contagious obligate parasite of the udder in
dairy cows. Here, we examined S. agalactiae-host interactions in bovine mammary epithelial …

Ras-related protein in brain (Rab) proteins are dysregulated in cancer cells and affect the
proliferation and metastasis of cancer cells, thereby reducing the survival rate of cancer …

The metastatic cascade is a complex process with multiple factors contributing to the
seeding and growth of cancer cells at metastatic sites. Within this complex process, several …