Natural withanolides, an update

G Xia, S Cao, L Chen, F Qiu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705
This review summarizes the latest progress and perspectives on the structural classification …

The genus Datura L.(Solanaceae): a systematic review of botany, traditional use, phytochemistry, pharmacology, and toxicology

W Lian, Y Wang, J Zhang, Y Yan, C Xia, H Gan… - Phytochemistry, 2022 - Elsevier
The genus Datura has been used as an important traditional medicine in China, as well as
in other countries worldwide. This review summarizes the latest progress and perspective of …

[PDF][PDF] Fungicidal potential of leaf extract of Datura metel L. to control Sclerotium rolfsii Sacc

N Jabeen, IH Khan, A Javaid - Allelopathy J, 2022 - researchgate.net
Sclerotium rolfii Sacc. causes collar rot disease in bell pepper (Capsicum annuum L.) that
results in significant yield losses. Since use of fungicides causes environmental pollution …

Recent advances in the chemistry and therapeutic evaluation of naturally occurring and synthetic withanolides

A Singh, A Raza, S Amin, C Damodaran, AK Sharma - Molecules, 2022 - mdpi.com
Natural products are a major source of biologically active compounds that make promising
lead molecules for developing efficacious drug-like molecules. Natural withanolides are …

Docking analysis of some bioactive compounds from traditional plants against SARS-CoV-2 target proteins

NM Abd El-Aziz, I Khalifa, AMG Darwish, AN Badr… - Molecules, 2022 - mdpi.com
COVID-19 is still a global pandemic that has not been stopped. Many traditional medicines
have been demonstrated to be incredibly helpful for treating COVID-19 patients while …

Withanolides isolated from Tubocapsicum anomalum and their antiproliferative activity

K Xiang, C Li, MX Li, ZR Song, XX Ma, DJ Sun, H Li… - Bioorganic …, 2021 - Elsevier
Abstract Seven undescribed withanolides (1–7) and six artificial withanolides (8–13), along
with 20 known compounds (14–33) were isolated from the aerial parts of Tubocapsicum …

[HTML][HTML] Secondary metabolites and biological profiles of Datura genus

C Céspedes-Méndez, P Iturriaga-Vásquez… - Journal of the Chilean …, 2021 - SciELO Chile
Solanaceae is an important family of plants where many species of this family are source for
food, industrial products, ornamental and medicinal uses. Within the family of Solanaceae …

Datura metel: A review on chemical constituents, traditional uses and pharmacological activities

W Alam, H Khan, SA Khan, S Nazir… - Current pharmaceutical …, 2021 - ingentaconnect.com
Datura metel (Solanaceae) which is commonly known as thorn's apple, Indian apple or
devil's trumpet isan annual herb of temperate zones which is distributed all over the world …

Integrated serum metabolomics and network pharmacology approach to reveal the potential mechanisms of withanolides from the leaves of Datura metel L. on …

Y Cheng, Y Liu, J Tan, Y Sun, W Guan, P Jiang… - … of Pharmaceutical and …, 2020 - Elsevier
Psoriasis is a chronic, immune-mediated inflammatory skin disease and highly depends on
inflammation and angiogenesis as well as other pathways. Our previous study showed that …

The chemical constituents of Diaphragma Juglandis Fructus and their inhibitory effect on α-Glucosidase activity

J Tan, Y Cheng, S Wang, J Li, H Ren, Y Qiao, Q Li… - Molecules, 2022 - mdpi.com
In our current investigation, 37 constituents (1–37), including 11 megastigmanes (1–11), 17
flavonoids (12–28) and 9 phenylpropanoids (29–37), were isolated from a 70%-EtOH extract …