3D in vitro corneal models: a review of current technologies

TM Shiju, RC de Oliveira, SE Wilson - Experimental eye research, 2020 - Elsevier
Abstract Three-dimensional (3D) in vitro models are excellent tools for studying complex
biological systems because of their physiological similarity to in vivo studies, cost …

Application of elastography for the noninvasive assessment of biomechanics in engineered biomaterials and tissues

W Kim, VL Ferguson, M Borden, CP Neu - Annals of biomedical …, 2016 - Springer
The elastic properties of engineered biomaterials and tissues impact their post-implantation
repair potential and structural integrity, and are critical to help regulate cell fate and gene …

Imaging corneal biomechanical responses to ocular pulse using high-frequency ultrasound

E Pavlatos, H Chen, K Clayson… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Imaging corneal biomechanical changes or abnormalities is important for better clinical
diagnosis and treatment of corneal diseases. We propose a novel ultrasound-based …

[HTML][HTML] Ocular pulse elastography: imaging corneal biomechanical responses to simulated ocular pulse using ultrasound

K Clayson, E Pavlatos, X Pan… - … Vision Science & …, 2020 - iovs.arvojournals.org
Purpose: In vivo evaluation of corneal biomechanics holds the potential for improving
diagnosis and management of ocular diseases. We aimed to develop an ocular pulse …

Measurement of corneal elasticity with an acoustic radiation force elasticity microscope

E Mikula, K Hollman, D Chai, JV Jester… - Ultrasound in medicine & …, 2014 - Elsevier
To investigate the role of collagen structure in corneal biomechanics, measurement of
localized corneal elasticity with minimal destruction to the tissue is necessary. We adopted …

Material properties from air puff corneal deformation by numerical simulations on model corneas

N Bekesi, C Dorronsoro, A de la Hoz, S Marcos - PLoS One, 2016 - journals.plos.org
Objective To validate a new method for reconstructing corneal biomechanical properties
from air puff corneal deformation images using hydrogel polymer model corneas and …

Mapping 3D strains with ultrasound speckle tracking: method validation and initial results in porcine scleral inflation

B Cruz Perez, E Pavlatos, HJ Morris, H Chen… - Annals of biomedical …, 2016 - Springer
This study aimed to develop and validate a high frequency ultrasound method for measuring
distributive, 3D strains in the sclera during elevations of intraocular pressure. A 3D cross …

Optic nerve head damage relation to intracranial pressure and corneal properties of eye in glaucoma risk assessment

C Kharmyssov, YG Abdildin, KV Kostas - Medical & Biological …, 2019 - Springer
This work presents results from numerical simulations of optic nerve head's (ONH)
biomechanical behavior during exposure to elevated intraocular (IOP) and/or intracranial …

In Vivo Corneal Biomechanical Properties in a Selected Chinese Population, Measured Using the Corneal Visualization Scheimpflug Technology

Y Li, L Tian, LL Guo, Y Hao, Y Jie - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Purpose: To evaluate the repeatability and reproducibility of recalculated dynamic corneal
response (DCR) parameters and the biomechanical-compensated intraocular pressure …

Spatially heterogeneous corneal mechanical responses before and after riboflavin–ultraviolet-A crosslinking

JR Palko, J Tang, BC Perez, X Pan, J Liu - Journal of Cataract & Refractive …, 2014 - Elsevier
Purpose To determine the heterogeneous through-thickness strains in the cornea at
physiologic intraocular pressures before and after corneal collagen crosslinking (CXL) using …