What is the general action of ghrelin for vertebrates?–Comparisons of ghrelin's effects across vertebrates

H Kaiya, K Kangawa, M Miyazato - General and Comparative …, 2013 - Elsevier
Ten years and more passed since ghrelin was discovered. Various physiological actions of
ghrelin have been documented in both mammalian and nonmammalian vertebrates. Do …

Ghrelin receptors in non-mammalian vertebrates

H Kaiya, K Kangawa, M Miyazato - Frontiers in Endocrinology, 2013 - frontiersin.org
The growth hormone secretagogue-receptor (GHS-R) was discovered in humans and pigs
in 1996. The endogenous ligand, ghrelin, was discovered 3 years later, in 1999, and our …

Immunohistochemical Characterization of PepT1 and Ghrelin in Gastrointestinal Tract of Zebrafish: Effects of Spirulina Vegetarian Diet on the Neuroendocrine System …

P Lo Cascio, C Calabrò, C Bertuccio, C Iaria… - Frontiers in …, 2018 - frontiersin.org
Gastrointestinal function in vertebrates is influenced by stressors, such as fasting and
refeeding, different types of diet and hormonal factors. The aim of this paper was to analyze …

Molecular evolution of GPCRs: Ghrelin/ghrelin receptors

H Kaiya, K Kangawa… - Journal of molecular …, 2014 - jme.bioscientifica.com
After the discovery in 1996 of the GH secretagogue-receptor type-1a (GHS-R1a) as an
orphan G-protein coupled receptor, many research groups attempted to identify the …

Effects of ghrelin and motilin on smooth muscle contractility of the isolated gastrointestinal tract from the bullfrog and Japanese fire belly newt

T Kitazawa, M Shimazaki, A Kikuta, N Yaosaka… - General and …, 2016 - Elsevier
Ghrelin has been identified in some amphibians and is known to stimulate growth hormone
release and food intake as seen in mammals. Ghrelin regulates gastrointestinal motility in …

Molecular cloning, regulation, and functional analysis of two GHS-R genes in zebrafish

JI Eom, A Hong, YH Kang, HJ Yoo, EJ Chang… - Experimental Cell …, 2014 - Elsevier
Mammalian ghrelin is derived from stomach and regulates growth hormone release and
appetite by modulating GHS-R (Growth hormone secretagogue receptor) activity. Zebrafish …

The octanoylated energy regulating hormone ghrelin: An expanded view of ghrelin's biological interactions and avenues for controlling ghrelin signaling

ER Cleverdon, KR McGovern-Gooch… - Molecular Membrane …, 2016 - Taylor & Francis
Ghrelin is a small peptide hormone that requires a unique post-translational modification,
serine octanoylation, to bind and activate the GHS-R1a receptor. Initially demonstrated to …

Stimulatory effect of ghrelin on food intake in bullfrog larvae

S Shimizu, H Kaiya, K Matsuda - Peptides, 2014 - Elsevier
Ghrelin is a potent orexigenic peptide implicated in appetite regulation in rodents. However,
except for teleost fish, the involvement of ghrelin in the regulation of feeding in non …

A genome-wide association study and an accurate genotyping strategy to identify and validate the SNPs related to the larval period in bullfrog Aquarana catesbeiana

Y Wang, G Wang, L Zhang, W Xu, G Zhang… - Aquaculture …, 2024 - Springer
Metamorphosis is the vital biological and morphologic process in economic amphibian
bullfrog Aquarana catesbeiana, and is usually quantified by larval period in actual seeding …

Diversification and coevolution of the ghrelin/growth hormone secretagogue receptor system in vertebrates

M Tine, H Kuhl, PR Teske, MH Tschöp… - Ecology and …, 2016 - Wiley Online Library
The gut hormone ghrelin is involved in numerous metabolic functions, such as the
stimulation of growth hormone secretion, gastric motility, and food intake. Ghrelin is modified …