Continuous spermatogenesis in post-pubertal mammals is dependent on spermatogonial
stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with …

Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …

The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …

This review addresses current understanding of the germline stem cell niche unit in
mammalian testes. Spermatogenesis is a classic model of tissue-specific stem cell function …

Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …

This article will provide an updated review of spermatogonial stem cells and their role in
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …

This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

Spermatogenesis is a classic model of cycling cell lineages that depend on a balance
between stem cell self-renewal for continuity and the formation of progenitors as the initial …

Continual spermatogenesis at a quantitatively normal level is required to sustain male
fertility. The foundation of this process relies on maintenance of an undifferentiated …