Objectives: Hemophagocytic lymphohistiocytosis is a cytokine release syndrome caused by
uncontrolled immune activation resulting in multiple organ failure and death. In this …

The HLH-2004 criteria were initially conceived as inclusion criteria for a clinical trial
investigating therapy for (largely primary) pediatric hemophagocytic lymphohistiocytosis …

Background Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal
hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the …

Objective: Hyperferritinemia is frequently seen in critically ill patients. A rather rare though
life-threatening condition related to severely elevated ferritin is hemophagocytic …

Timely diagnosis of hemophagocytic lymphohistiocytosis (HLH) is critical and relies on
clinical judgment. The HLH‐2004 criteria are commonly used diagnostic criteria, whereas …

Background: Hemophagocytic lymphohistiocytosis (HLH), an uncontrolled overactivation of
the immune system, is well characterized in pediatric patients, yet, much less is known about …

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal hyperinflammatory
syndrome occurring in genetically succeptibe individuals, which results due to hyperactive …

Secondary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening immune
dysregulation disorder. Use of chimeric antigen receptor T-cell therapy (CAR-T) is …

儿童噬血性淋巴组织细胞增多症诊治进展∗ Page 1 临床血液学杂志 2022年 JClinHematol(China)
35卷1期 儿童噬血性淋巴组织细胞增多症诊治进展∗ …

Introduction Secondary hemophagocytic syndrome (HPS) and systemic inflammatory
response syndrome (SIRS) share similar clinical findings as a result of hyperinflammation …