[HTML][HTML] Drug repurposing strategies in the development of potential antifungal agents
Q Zhang, F Liu, M Zeng, Y Mao, Z Song - Applied Microbiology and …, 2021 - Springer
The morbidity and mortality caused by invasive fungal infections are increasing across the
globe due to developments in transplant surgery, the use of immunosuppressive agents …
globe due to developments in transplant surgery, the use of immunosuppressive agents …
[HTML][HTML] Chemosensitization as a means to augment commercial antifungal agents
BC Campbell, KL Chan, JH Kim - Frontiers in microbiology, 2012 - frontiersin.org
Antimycotic chemosensitization and its mode of action are of growing interest. Currently, use
of antifungal agents in agriculture and medicine has a number of obstacles. Foremost of …
of antifungal agents in agriculture and medicine has a number of obstacles. Foremost of …
[HTML][HTML] Antifungal drug repurposing
JH Kim, LW Cheng, KL Chan, CC Tam, N Mahoney… - Antibiotics, 2020 - mdpi.com
Control of fungal pathogens is increasingly problematic due to the limited number of
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …
[HTML][HTML] Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans
S Liu, L Yue, W Gu, X Li, L Zhang, S Sun - PloS one, 2016 - journals.plos.org
Candidiasis has increased significantly recently that threatens patients with low immunity.
However, the number of antifungal drugs on the market is limited in comparison to the …
However, the number of antifungal drugs on the market is limited in comparison to the …
[HTML][HTML] Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis
H Bar-Yosef, N Vivanco Gonzalez, S Ben-Aroya… - Scientific reports, 2017 - nature.com
Candida albicans is an opportunistic pathogen, typically found as a benign commensal
yeast living on skin and mucosa, but poised to invade injured tissue to cause local …
yeast living on skin and mucosa, but poised to invade injured tissue to cause local …
Gênero Candida-Fatores de virulência, epidemiologia, candidíase e mecanismos de resistência
WRV da Rocha, LE Nunes, MLR Neves… - Research, Society and …, 2021 - rsdjournal.org
The genus Candida is found symbiotically living in the microbiota of the reproductive and
gastrointestinal mucosa of 50-70% of healthy individuals, under certain conditions these …
gastrointestinal mucosa of 50-70% of healthy individuals, under certain conditions these …
The role of drug efflux pumps in Malassezia pachydermatis and Malassezia furfur defence against azoles
R Iatta, MR Puttilli, D Immediato, D Otranto… - Mycoses, 2017 - Wiley Online Library
This study aims to evaluate the effect of efflux pump modulators (EPM s) on the minimal
inhibitory concentration (MIC) of fluconazole (FLZ) and voriconazole (VOR) in Malassezia …
inhibitory concentration (MIC) of fluconazole (FLZ) and voriconazole (VOR) in Malassezia …
In vitro synergistic effects of chlorpromazine and sertraline in combination with amphotericin B against Cryptococcus neoformans var. grubii
L Rossato, ÉS Loreto, RA Zanette, F Chassot… - Folia microbiologica, 2016 - Springer
Cryptococcus neoformans is encapsulated yeast that causes cryptococcosis. The
cryptococcal meningitis may cause neuropsychiatric symptoms. Here, we evaluated the in …
cryptococcal meningitis may cause neuropsychiatric symptoms. Here, we evaluated the in …
Novel avenues for identification of new antifungal drugs and current challenges
J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
[HTML][HTML] Acetaminophen levels found in recycled wastewater alter soil microbial community structure and functional diversity
NK McLain, MY Gomez, EW Gachomo - Microbial ecology, 2023 - Springer
The practice of using recycled wastewater (RWW) has been successfully adopted to address
the growing demand for clean water. However, chemicals of emerging concern (CECs) …
the growing demand for clean water. However, chemicals of emerging concern (CECs) …