Bicyclic β-amino acids
OO Grygorenko - Tetrahedron, 2015 - Elsevier
The field of β-amino acids and β-peptides has given rise to considerable interest in recent
decades. 1, 1 (a), 1 (b), 1 (c), 1 (d), 1 (e), 1 (f) β-Amino acids are widespread in the nature as …
decades. 1, 1 (a), 1 (b), 1 (c), 1 (d), 1 (e), 1 (f) β-Amino acids are widespread in the nature as …
Synthesis of thiadiazabicyclane and bis-1, 3, 5-dithiazinane by cyclothiomethylation of aliphatic diamines with CH2O and H2S
VR Akhmetova, RA Vagapov, GR Nadyrgulova… - Tetrahedron, 2007 - Elsevier
Cyclocondensation of aliphatic diamines with CH2O and H2S (1: 3: 2 ratio, 0° C) was carried
out to give thiadiazabicyclanes and dithiadiazabicyclanes (1: 6: 4 ratio), which were …
out to give thiadiazabicyclanes and dithiadiazabicyclanes (1: 6: 4 ratio), which were …
Synthesis of tricyclic analogues of methyllycaconitine using ring closing metathesis to append a B ring to an AE azabicyclic fragment
The synthesis of several ABE tricyclic analogues of the alkaloid methyllycaconitine 1 is
reported. The analogues contain two key pharmacophores: a homocholine motif formed …
reported. The analogues contain two key pharmacophores: a homocholine motif formed …
Efficient synthesis of the azabicyclo [3.3. 1] nonane ring system in the alkaloid methyllycaconitine using bis (alkoxymethyl) alkylamines as aminoalkylating agents in a …
MA Brimble, C Brocke - 2005 - Wiley Online Library
The double Mannich reaction of cyclic β‐keto esters with bis (alkoxymethyl) alkylamines
provides an efficient and versatile method for the construction of azabicyclo [3.3. 1] nonanes …
provides an efficient and versatile method for the construction of azabicyclo [3.3. 1] nonanes …
2, 4-Diaryl-3-azabicyclo [3.3. 1] nonan-9-ones with tert-pentyl substituent on the cyclohexane: Complete NMR spectral study
P Parthiban, J Dineshkumar, DH Park - Journal of Molecular Structure, 2024 - Elsevier
A series of 7‑tert-pentyl-2, 4-diaryl-3-azabicyclo [3.3. 1] nonan-9-ones (5-11), as well as
three reported analogs (1, 2 and 4) were synthesized, and characterized under identical …
three reported analogs (1, 2 and 4) were synthesized, and characterized under identical …
1H and 13C NMR data for C‐6 substituted 3‐azabicyclo[3.3.1]nonane‐1‐carboxylates
KJ Goodall, MA Brimble… - Magnetic Resonance in …, 2006 - Wiley Online Library
Abstract The 1H and 13C NMR spectra of 3‐azabicyclo [3.3. 1] nonanes with various
oxygenated substituents at C‐6 were assigned using 1D (DEPT) and 2D (COSY, HSQC …
oxygenated substituents at C‐6 were assigned using 1D (DEPT) and 2D (COSY, HSQC …
Spectroscopic, Structural, and Computational Characterization of Three Bispidinone Derivatives, as Ligands for Enantioselective Metal Catalyzed Reactions
C Castellano, A Sacchetti, F Meneghetti - Chirality, 2016 - Wiley Online Library
Three chiral derivatives of the alkaloid sparteine (bispidines), characterized by the 3, 7‐
diazabicyclo [3.3. 1] nonane moiety, were designed as efficient ligands in a number of …
diazabicyclo [3.3. 1] nonane moiety, were designed as efficient ligands in a number of …
Synthesis of N‐(3‐Phenylpropyl)‐Substituted Tricyclic ABE Ring Analogues of the Alkaloid Methyllycaconitine
A Lehmann, C Brocke, D Barker, MA Brimble - 2006 - Wiley Online Library
The synthesis of several ABE tricyclic analogues 5, 31 and 32 of the alkaloid
methyllycaconitine (1) is reported. The analogues contain two key pharmacophores: a …
methyllycaconitine (1) is reported. The analogues contain two key pharmacophores: a …
Stereoselective synthesis of 4-substituted 4-hydroxypiperidines via epoxidation-ring opening of 4-methylenepiperidines
VA McKay, SJ Thompson, PM Tran, KJ Goodall… - Synlett, 2010 - thieme-connect.com
Abstract Reaction of 9-methylene-3-azabicyclo [3.3. 1] nonanes with trifluoroperacetic acid
results in stereoselective epoxidation to give the syn-epoxide. Intermolecular hydrogen …
results in stereoselective epoxidation to give the syn-epoxide. Intermolecular hydrogen …
5, 6-Membered CNN palladium pincer complexes of 3-benzyl-8-dimethylamino-3-azabicyclo [3.2. 1] octane and 3-benzyl-9-dimethylamino-3-azabicyclo [3.3. 1] …
LA Bulygina, NS Khrushcheva, KA Lyssenko… - Journal of …, 2019 - Elsevier
The unsymmetrical CNN pincer ligand precursors 4 and 7b based on the structures of
bicyclo [3.2. l] octane and bicyclo [3.3. l] nonane have been synthesized. The corresponding …
bicyclo [3.2. l] octane and bicyclo [3.3. l] nonane have been synthesized. The corresponding …