[HTML][HTML] Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway

M Tufail, JJ Hu, J Liang, CY He, WD Wan… - Journal of Translational …, 2024 - Springer
Breast cancer (BC) is a multifaceted disease characterized by distinct molecular subtypes
and varying responses to treatment. In BC, the phosphatidylinositol 3-kinase (PI3K) pathway …

Clinical Use of Molecular Biomarkers in Canine and Feline Oncology: Current and Future

H Aupperle-Lellbach, A Kehl, S de Brot… - Veterinary …, 2024 - mdpi.com
Simple Summary Molecular biomarkers in cancer are measurable genomic alterations that
can indicate the risk of developing neoplasia, the presence of neoplastic cells, patient …

Wortmannin Inhibits Cell Growth and Induces Apoptosis in Colorectal Cancer Cells by Suppressing the PI3K/AKT Pathway

N Bani, F Rahmani, N Shakour… - Anti-Cancer Agents …, 2024 - ingentaconnect.com
Background: Colorectal cancer (CRC) remains a significant contributor to mortality, often
exacerbated by metastasis and chemoresistance. Novel therapeutic strategies are …

Association of Orai1 and Peizo1 genes expression with cellular proliferation, metastasis and angiogenesis biomarkers in colon tumor biopsies of CRC patients

F Awla, G Othman - Cellular and Molecular Biology, 2023 - mail.cellmolbiol.org
Colon cancer is a complex malignancy characterized by intricate molecular interactions that
influence its progression. This study investigates the role of calcium channel gene …

Somatic mutational profiling and clinical impact of driver genes in Latin‐Iberian medulloblastomas: Towards precision medicine

LGRP Barateiro, R de Oliveira Cavagna… - … - Wiley Online Library
Medulloblastoma (MB) is the most prevalent malignant brain tumor in children, known for its
heterogeneity and treatment‐associated toxicity, and there is a critical need for new …