St. Jude Cloud: a pediatric cancer genomic data-sharing ecosystem
Effective data sharing is key to accelerating research to improve diagnostic precision,
treatment efficacy, and long-term survival in pediatric cancer and other childhood …
treatment efficacy, and long-term survival in pediatric cancer and other childhood …
A program of transition to adult care for sickle cell disease
AC Saulsberry, JS Porter… - Hematology 2014, the …, 2019 - ashpublications.org
Most children with sickle cell disease (SCD) today survive into adulthood. Among emerging
adults, there is a marked increase in acute care utilization and a rise in mortality, which can …
adults, there is a marked increase in acute care utilization and a rise in mortality, which can …
Sickle cell nephropathy in the pediatric population
Background: Compared to the past, patients with sickle cell disease (SCD) currently live
longer due to improvements in diagnosis and comprehensive care. Due to these advances …
longer due to improvements in diagnosis and comprehensive care. Due to these advances …
Hydroxyurea treatment and neurocognitive functioning in sickle cell disease from school age to young adulthood
AM Heitzer, J Longoria, V Okhomina… - British journal of …, 2021 - Wiley Online Library
Neurocognitive impairment is common in sickle cell disease (SCD) and is associated with
significant functional limitations. In a cross‐sectional analysis, we examined the association …
significant functional limitations. In a cross‐sectional analysis, we examined the association …
[HTML][HTML] Development of the incharge health mobile app to improve adherence to hydroxyurea in patients with sickle cell disease: user-centered design approach
Background Sickle cell disease (SCD) is an inherited blood disorder causing acute
complications and chronic progressive end organ damage. SCD is associated with …
complications and chronic progressive end organ damage. SCD is associated with …
Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy
JD Lebensburger, I Aban, B Pernell… - American journal of …, 2019 - Wiley Online Library
Background In patients with diabetes mellitus, hyperfiltration precedes the development of
albuminuria. Pediatric sickle cell anemia (SCA) patients have a high prevalence of …
albuminuria. Pediatric sickle cell anemia (SCA) patients have a high prevalence of …
Genetic variants associated with therapy-related cardiomyopathy among childhood cancer survivors of African ancestry
Cardiomyopathy occurs at significantly higher rates in survivors of childhood cancer than the
general population, but few studies have evaluated racial or ethnic disparities, and none …
general population, but few studies have evaluated racial or ethnic disparities, and none …
[HTML][HTML] Establishing a sickle cell disease registry in Africa: experience from the Sickle Pan-African Research Consortium, Kumasi-Ghana
Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …
characterized by painful episodes, anemia, high risk of infection, and other acute and …
Longitudinal effect of disease‐modifying therapy on left ventricular diastolic function in children with sickle cell anemia
P Rai, VI Okhomina, G Kang… - American Journal of …, 2023 - Wiley Online Library
Cardiac abnormalities seen in sickle cell anemia (SCA) include diastolic dysfunction, which
has been shown to be associated with high morbidity and early mortality. The effect of …
has been shown to be associated with high morbidity and early mortality. The effect of …
[HTML][HTML] Publication of data collection forms from NHLBI funded sickle cell disease implementation consortium (SCDIC) registry
JA Glassberg, EA Linton, K Burson… - Orphanet journal of rare …, 2020 - Springer
Background Sickle cell disease (SCD) is an autosomal recessive blood disorder affecting
approximately 100,000 Americans and 3.1 million people globally. The scarcity of relevant …
approximately 100,000 Americans and 3.1 million people globally. The scarcity of relevant …