Over a century ago, the phenothiazine dye, methylene blue, was discovered to have both
antipsychotic and anti-cancer effects. In the 20th-century, the first phenothiazine …

The rising global burden of cancer has driven considerable efforts into the research and
development of effective anti-cancer agents. Fortunately, with impressive advances in …

Introduction: Bivalve molluscs like Mytilus galloprovincialis are valuable bioindicators due to
their filter-feeding lifestyle, wide distribution, and ability to concentrate xenobiotics. Studying …

The rapid fabrication is described of binary electrocatalyst based on a highly porous metal–
organic framework with zirconium metal core (Zr-MOF) decorated over the graphitic carbon …

In this review, we summarized the current literature on the impact of phenothiazine
derivatives on autophagy in vitro. Phenothiazines are antipsychotic drugs used in the …

Cancer is a pernicious and pressing medical problem; moreover, it is a failure of
multicellular morphogenesis that sheds much light on evolutionary developmental biology …

Cancer is recognized as the major cause of death worldwide and the most challenging
public health issues. Tumor cells exhibit molecular adaptations and metabolic reprograming …

The potential benefits of drug repurposing have gained attention as an alternative to
developing de novo drugs. The potential of using central nervous system (CNS) drugs as …

Gliomas constitute a diverse and complex array of tumors within the central nervous system
(CNS), characterized by a wide range of prognostic outcomes and responses to therapeutic …

The abnormal progression of tumors has been a problem for treatment of cancer and
therapeutic should be directed towards targeting main mechanisms involved in …