Importance Uncontrolled and indiscriminate prescribing of opioids has led to an opioid crisis
that started in North America and spread throughout high-income countries. The aim of this …

Obstructive sleep apnea (OSA) is a highly prevalent disorder that has profound implications
on the outcomes of patients with chronic lung disease. The hallmark of OSA is a collapse of …

This international multidisciplinary consensus statement was developed to provide balanced
guidance on the safe peri‐operative use of opioids in adults. An international panel of …

The majority of women undergoing cesarean delivery in the United States receive neuraxial
morphine, the most effective form of postoperative analgesia for this surgery. Current …

BACKGROUND: Obstructive sleep apnea (OSA) patients are at increased risk for pulmonary
and cardiovascular complications; perioperative mortality risk is unclear. This report …

Opioids and benzodiazepines are increasingly used alone or in combination. However, the
combined use of these agents increases the risk for potentially lethal respiratory depression …

Opioids are widely prescribed for pain management, and it is estimated that 40% of adults in
the United States use prescription opioids every year. Opioid misuse leads to high mortality …

The prevalence of obstructive sleep apnea (OSA) has reached 1 billion people worldwide,
implying significant risk for the perioperative setting as patients are vulnerable to …

Purpose Opioid-free anesthesia (OFA) is an alternative to conventional opioid-based
anesthesia (OBA) in patients undergoing bariatric surgery. Several small studies and a meta …

Opioid-induced respiratory depression (OIRD) and postoperative nausea and vomiting
(PONV) are challenging, resource-intensive, and costly opioid-related adverse events …