[HTML][HTML] Role of ROCK signaling in virus replication
Rho-associated protein kinase (ROCK) is a serine-threonine kinase and is a major
downstream effector of the small GTPaseRhoA. Upon activation, Rho/ROCK cell signaling …
downstream effector of the small GTPaseRhoA. Upon activation, Rho/ROCK cell signaling …
Potential therapeutic targets for Mpox: the evidence to date
SN Byrareddy, K Sharma, S Sachdev… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction The global Mpox (MPX) disease outbreak caused by the Mpox virus
(MPXV) in 2022 alarmed the World Health Organization (WHO) and health regulation …
(MPXV) in 2022 alarmed the World Health Organization (WHO) and health regulation …
Hesperetin blocks poxvirus replication with a low tendency to select for drug‐resistant viral variants
A Verma, RK Dedar, R Kumar… - Journal of Medical …, 2024 - Wiley Online Library
In this study, we demonstrated the antiviral efficacy of hesperetin against multiple
poxviruses, including buffalopox virus (BPXV), vaccinia virus (VACV), and lumpy skin …
poxviruses, including buffalopox virus (BPXV), vaccinia virus (VACV), and lumpy skin …
Targeting ARNT attenuates chemoresistance through destabilizing p38α-MAPK signaling in glioblastoma
Glioblastoma (GBM) is the most aggressive and lethal brain tumor in adults. This study
aimed to investigate the functional significance of aryl hydrocarbon receptor nuclear …
aimed to investigate the functional significance of aryl hydrocarbon receptor nuclear …
Evolutionary radiation strategy revealed in the Scarabaeidae with evidence of continuous spatiotemporal morphology and phylogenesis
Evolutionary biology faces the important challenge of determining how to interpret the
relationship between selection pressures and evolutionary radiation. The lack of …
relationship between selection pressures and evolutionary radiation. The lack of …
[HTML][HTML] Therapeutic potential of natural alkaloid emetine against emerging COVID-19 and future viral pandemics
B Dinda, S Dinda, M Dinda, IS Sarma… - European Journal of …, 2024 - Elsevier
The outbreak of COVID-19 pandemic caused by the infection of SARS-CoV-2, has become a
global crisis, threatening public health and disrupting global economy. Until now, effective …
global crisis, threatening public health and disrupting global economy. Until now, effective …
Buffalopox: An emerging zoonotic challenge
A Pattanaik, L Lodha, S Marate, K Dhanya… - Infectious Diseases …, 2024 - Elsevier
As a variant of Vaccinia virus, Buffalopox virus is known to cause Buffalopox. In recent times,
sporadic outbreaks of the infection in humans have been reported, especially in the endemic …
sporadic outbreaks of the infection in humans have been reported, especially in the endemic …
p38-MAPK is prerequisite for the synthesis of SARS-CoV-2 protein
P Mittal, N Khandelwal, Y Chander, A Verma, R Kumar… - VirusDisease, 2024 - Springer
The inhibition of p38 mitogen-activated protein kinase (p38-MAPK) by small molecule
chemical inhibitors was previously shown to impair severe acute respiratory syndrome …
chemical inhibitors was previously shown to impair severe acute respiratory syndrome …
Phytofabrication of Silver Nanoparticles Using Pomegranate Juice Extract for Antioxidant, Antimicrobial and Cytotoxic Activities
J Rani, S Singh, A Beniwal, M Moond… - …, 2024 - Wiley Online Library
In the current research, monowave‐assisted biosynthesis of AgNPs utilising aqueous
Pomegranate Juice extract (PJE) for antioxidant, antimicrobial and cytotoxic activities were …
Pomegranate Juice extract (PJE) for antioxidant, antimicrobial and cytotoxic activities were …
Hesperetin blocks poxvirus replication by competitively inhibiting binding of the 5'cap of viral mRNA with eIF4E
N Kumar, A Verma, RK Dedar, R Kumar… - Authorea …, 2023 - advance.sagepub.com
In this study, hesperetin was shown to inhibit the replication of multiple poxviruses, including
buffalopox virus (BPXV), vaccinia virus, and lumpy skin disease virus (LSDV). Hesperetin …
buffalopox virus (BPXV), vaccinia virus, and lumpy skin disease virus (LSDV). Hesperetin …