[HTML][HTML] Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

The first, holistic immunological model of COVID‐19: implications for prevention, diagnosis, and public health measures

PM Matricardi, RW Dal Negro… - Pediatric Allergy and …, 2020 - Wiley Online Library
The natural history of COVID‐19 caused by SARS‐CoV‐2 is extremely variable, ranging
from asymptomatic or mild infection, mainly in children, to multi‐organ failure, eventually …

[HTML][HTML] The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection

O Gallo, LG Locatello, A Mazzoni, L Novelli… - Mucosal …, 2021 - Elsevier
The novel coronavirus SARS-CoV-2 enters into the human body mainly through the ACE2+
TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a …

[HTML][HTML] Age and sex-associated changes of complement activity and complement levels in a healthy Caucasian population

M Gaya da Costa, F Poppelaars, C Van Kooten… - Frontiers in …, 2018 - frontiersin.org
Introduction: The complement system is essential for an adequate immune response. Much
attention has been given to the role of complement in disease. However, to better …

Cell death by phagocytosis

GC Brown - Nature Reviews Immunology, 2024 - nature.com
Cells can die as a consequence of being phagocytosed by other cells—a form of cell death
that has been called phagotrophy, cell cannibalism, programmed cell removal and primary …

N-glycomic biomarkers of biological aging and longevity: a link with inflammaging

F Dall'Olio, V Vanhooren, CC Chen, PE Slagboom… - Ageing research …, 2013 - Elsevier
Glycosylation is a frequent co/post-translational modification of proteins which modulates a
variety of biological functions. The analysis of N-glycome, ie the sugar chains N-linked to …

[HTML][HTML] COVID-19 and pediatric asthma: clinical and management challenges

JL Boechat, GF Wandalsen, FC Kuschnir… - International journal of …, 2021 - mdpi.com
Asthma is the most frequent chronic condition in childhood and a current concern exists
about asthma in the pediatric population and its risk for severe SARS-CoV-2 infection …

[HTML][HTML] Inflammaging and complement system: a link between acute kidney injury and chronic graft damage

R Franzin, A Stasi, M Fiorentino, G Stallone… - Frontiers in …, 2020 - frontiersin.org
The aberrant activation of complement system in several kidney diseases suggests that this
pillar of innate immunity has a critical role in the pathophysiology of renal damage of …

[HTML][HTML] Changes in dietary patterns and clinical health outcomes in different countries during the SARS-CoV-2 pandemic

R Filip, L Anchidin-Norocel, R Gheorghita, WK Savage… - Nutrients, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has led to an excess in community mortality across the globe …