A systematic review of antimicrobial resistance in Salmonella enterica serovar Typhi, the etiological agent of typhoid

CD Britto, VK Wong, G Dougan… - PLoS neglected tropical …, 2018 - journals.plos.org
Background The temporal and spatial change in trends of antimicrobial resistance (AMR) in
typhoid have not been systematically studied, and such information will be critical for …

Fluoroquinolone resistance in Salmonella: insights by whole-genome sequencing

WL Cuypers, J Jacobs, V Wong… - Microbial …, 2018 - microbiologyresearch.org
Fluoroquinolone (FQ)-resistant Salmonella spp. were listed by the WHO in 2017 as priority
pathogens for which new antibiotics were urgently needed. The overall global burden of …

Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones …

EJ Klemm, S Shakoor, AJ Page, FN Qamar, K Judge… - MBio, 2018 - Am Soc Microbiol
Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi, the causative
agent of typhoid. Multidrug-resistant (MDR) isolates are prevalent in parts of Asia and Africa …

Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

ME Carey, ZA Dyson, DJ Ingle, A Amir, MK Aworh… - Elife, 2023 - elifesciences.org
Background: The Global Typhoid Genomics Consortium was established to bring together
the typhoid research community to aggregate and analyse Salmonella enterica serovar …

The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study

KE da Silva, AM Tanmoy, AK Pragasam, J Iqbal… - The Lancet …, 2022 - thelancet.com
Background The emergence of increasingly antimicrobial-resistant Salmonella enterica
serovar Typhi (S Typhi) threatens to undermine effective treatment and control …

Antibiotic resistance and typhoid

ZA Dyson, EJ Klemm, S Palmer… - Clinical Infectious …, 2019 - academic.oup.com
Multiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of
typhoid and other infectious diseases. Since the 1970s, this threat has increased in …

Molecular mechanism of azithromycin resistance among typhoidal Salmonella strains in Bangladesh identified through passive pediatric surveillance

Y Hooda, MSI Sajib, H Rahman, SP Luby… - PLoS neglected …, 2019 - journals.plos.org
Background With the rise in fluoroquinolone-resistant Salmonella Typhi and the recent
emergence of ceftriaxone resistance, azithromycin is one of the last oral drugs available …

The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

SE Park, DT Pham, C Boinett, VK Wong, GD Pak… - Nature …, 2018 - nature.com
There is paucity of data regarding the geographical distribution, incidence, and
phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here …

A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at pathogenwatch

S Argimón, CA Yeats, RJ Goater, K Abudahab… - Nature …, 2021 - nature.com
As whole-genome sequencing capacity becomes increasingly decentralized, there is a
growing opportunity for collaboration and the sharing of surveillance data within and …

Dynamics of antimicrobial resistance in intestinal Escherichia coli from children in community settings in South Asia and sub-Saharan Africa

DJ Ingle, MM Levine, KL Kotloff, KE Holt… - Nature …, 2018 - nature.com
The dynamics of antimicrobial resistance (AMR) in developing countries are poorly
understood, especially in community settings, due to a sparsity of data on AMR prevalence …