Persistent neurological and neuropsychiatric symptoms affect a substantial fraction of
people after COVID-19 and represent a major component of the post-acute COVID-19 …

Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

Low-grade inflammation is a hallmark of old age and a central driver of ageing-associated
impairment and disease. Multiple factors can contribute to ageing-associated inflammation; …

All living things experience an increase in entropy, manifested as a loss of genetic and
epigenetic information. In yeast, epigenetic information is lost over time due to the …

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …

Most adult organs contain regenerative stem cells, often organized in specific niches. Stem
cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on …

Although SARS-CoV-2 primarily targets the respiratory system, patients with and survivors of
COVID-19 can suffer neurological symptoms 1, 2, 3. However, an unbiased understanding …

Contemporary studies have completely changed the view of brain immunity from envisioning
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …

A hallmark of nervous system aging is a decline of white matter volume and function, but the
underlying mechanisms leading to white matter pathology are unknown. In the present …

Ageing leads to profound alterations in the immune system and increases susceptibility to
some chronic, infectious and autoimmune diseases. In recent years, widespread application …