This review covers diastereo-and enantiodivergent catalyzed reactions in acyclic and cyclic
systems using metal complexes or organocatalysts. Among them, nucleophilic addition to …

1. INTRODUCTION Despite being largely absent from natural products and biological
processes, fluorine plays a conspicuous and increasingly important role within …

In contrast to the widely explored methods for the asymmetric synthesis of molecules
bearing a single stereocenter or adjacent stereocenters, the concurrent construction of 1, 3 …

Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

This Perspective presents an overview of catalytic enantioselective transformations that
allow convenient access to all stereoisomers of a given product with multiple stereogenic …

Asymmetric organocatalysis has experienced a long and spectacular way since the early
reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small …

An unprecedented hydroalkylation of racemic allylic alcohols and racemic ketimine esters
enabled by Cu/Ru relay catalysis has been developed via merging the ruthenium‐catalyzed …

The structural complexity of glycans poses a serious challenge in the chemical synthesis of
glycosides, oligosaccharides and glycoconjugates. Glycan complexity, determined by …

An important challenge in asymmetric synthesis is the development of fully stereodivergent
strategies to access the full complement of stereoisomers of products bearing multiple …

Herein, we report a synthesis of cyclohexanones bearing multi‐continuous stereocenters by
combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to cyclic …