The development of antibiotic resistance in Staphylococcus aureus, particularly in methicillin-
resistant S. aureus (MRSA), has become a significant health concern worldwide. The …

The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …

Interbacterial antagonism and associated defensive strategies are both essential during
bacterial competition. The human gut symbiont Bacteroides fragilis secretes a ubiquitin …

Antibiotics, considered a “wonder medication” in the 20th century, have been exploited to
such an extent that bacteria have developed resistance against them giving rise to highly …

Most clinical MRSA (methicillin-resistant S. aureus) isolates exhibit low-level β-lactam
resistance (oxacillin MIC 2–4 μg/ml) due to the acquisition of a novel penicillin binding …

Methicillin‐resistant Staphylococcus aureus (MRSA) is resistant to most β‐lactams due to
the expression of an extra penicillin‐binding protein, PBP2a, with low β‐lactam affinity. It has …

The function of many bacterial processes depends on the formation of functional membrane
microdomains (FMMs), which resemble the lipid rafts of eukaryotic cells. However, the …

The development of resistance to β-lactam antibiotics has made Staphylococcus aureus a
clinical burden on a global scale. MRSA (methicillin-resistant S. aureus) is commonly known …

Staphylococcus aureus is a major pathogen, which colonizes one in three otherwise healthy
humans. This significant spread of S. aureus is largely due to its ability to circumvent innate …

Two naphthoquinone-derived heterodimers with unprecedented carbon skeletons,
eleucanainones A (1) and B (2), were isolated from the bulbs of Eleutherine americana …