Lipogenesis inhibitors: therapeutic opportunities and challenges
B Batchuluun, SL Pinkosky, GR Steinberg - Nature Reviews Drug …, 2022 - nature.com
Fatty acids are essential for survival, acting as bioenergetic substrates, structural
components and signalling molecules. Given their vital role, cells have evolved mechanisms …
components and signalling molecules. Given their vital role, cells have evolved mechanisms …
Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases
J Gutiérrez-Cuevas, A Santos… - International Journal of …, 2021 - mdpi.com
Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …
Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis
H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …
representing the most common chronic liver disease in the world. Atherosclerotic …
Current status and future trends of the global burden of MASLD
L Miao, G Targher, CD Byrne, YY Cao… - Trends in Endocrinology & …, 2024 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most
common chronic liver disease globally, affecting more than a third of the world's adult …
common chronic liver disease globally, affecting more than a third of the world's adult …
[HTML][HTML] Metabolic-associated fatty liver disease (MAFLD): a multi-systemic disease beyond the liver
Nonalcoholic fatty liver disease (NAFLD) is a multisystemic clinical condition that presents
with a wide spectrum of extrahepatic manifestations, such as obesity, type 2 diabetes …
with a wide spectrum of extrahepatic manifestations, such as obesity, type 2 diabetes …
A meta-analysis on the global prevalence, risk factors and screening of coronary heart disease in nonalcoholic fatty liver disease
JZK Toh, XH Pan, PWL Tay, CH Ng, JN Yong… - Clinical …, 2022 - Elsevier
Background & Aims Cardiovascular disease remains the leading cause of death in patients
with nonalcoholic fatty liver disease (NAFLD). Studies examining the association of coronary …
with nonalcoholic fatty liver disease (NAFLD). Studies examining the association of coronary …
Risk of cardiovascular events in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis
Aims Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent disease and has been
repeatedly associated with an increased risk of cardiovascular disease. However, the extent …
repeatedly associated with an increased risk of cardiovascular disease. However, the extent …
Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver …
Non-alcoholic fatty liver disease (NAFLD) is common, affecting approximately 25% of the
general population. The evidence base for the investigation and management of NAFLD is …
general population. The evidence base for the investigation and management of NAFLD is …
[HTML][HTML] An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
DQ Sun, G Targher, CD Byrne… - … surgery and nutrition, 2023 - ncbi.nlm.nih.gov
Background With the rising global prevalence of fatty liver disease related to metabolic
dysfunction, the association of this common liver condition with chronic kidney disease …
dysfunction, the association of this common liver condition with chronic kidney disease …
Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies
E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
In recent years, the incidence of non-viral hepatocellular carcinoma (HCC) has increased
dramatically, which is probably related to the increased prevalence of metabolic syndrome …
dramatically, which is probably related to the increased prevalence of metabolic syndrome …