Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …
distressing memories, is a chronic debilitating condition in need of new treatment options …
C‐reactive protein: Marker of risk for post‐traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery
SF Friend, R Nachnani, SB Powell… - European Journal of …, 2022 - Wiley Online Library
Increasing evidence indicates that inflammation plays a role in PTSD and stress disorder
pathophysiology. PTSD is consistently associated with higher circulating inflammatory …
pathophysiology. PTSD is consistently associated with higher circulating inflammatory …
Whole genome sequence analysis of the plasma proteome in black adults provides novel insights into cardiovascular disease
Background: Plasma proteins are critical mediators of cardiovascular processes and are the
targets of many drugs. Previous efforts to characterize the genetic architecture of the plasma …
targets of many drugs. Previous efforts to characterize the genetic architecture of the plasma …
Genome-wide association studies of schizophrenia and bipolar disorder in a diverse cohort of US veterans
Background Schizophrenia (SCZ) and bipolar disorder (BIP) are debilitating
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …
[HTML][HTML] Analysis of genetically regulated gene expression identifies a prefrontal PTSD gene, SNRNP35, specific to military cohorts
To reveal post-traumatic stress disorder (PTSD) genetic risk influences on tissue-specific
gene expression, we use brain and non-brain transcriptomic imputation. We impute …
gene expression, we use brain and non-brain transcriptomic imputation. We impute …
Mitochondrial DNA as a marker for treatment-response in post-traumatic stress disorder
EM Hummel, K Piovesan, F Berg, S Herpertz… - …, 2023 - Elsevier
Post-traumatic stress disorder (PTSD) is a serious mental health condition thought to be
mediated by a dysregulated stress response system. Stress, especially chronic stress …
mediated by a dysregulated stress response system. Stress, especially chronic stress …
[HTML][HTML] From genetics to systems biology of stress-related mental disorders
Many individuals will be exposed to some form of traumatic stress in their lifetime which, in
turn, increases the likelihood of developing stress-related disorders such as post-traumatic …
turn, increases the likelihood of developing stress-related disorders such as post-traumatic …
[HTML][HTML] Mineralocorticoid receptor and glucocorticoid receptor work alone and together in cell-type-specific manner: Implications for resilience prediction and targeted …
Abstract 'You can't roll the clock back and reverse the effects of experiences' Bruce McEwen
used to say when explaining how allostasis labels the adaptive process. Here we will for …
used to say when explaining how allostasis labels the adaptive process. Here we will for …
PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L
Posttraumatic stress disorder (PTSD) is characterized by intrusive thoughts, avoidance,
negative alterations in cognitions and mood, and arousal symptoms that adversely affect …
negative alterations in cognitions and mood, and arousal symptoms that adversely affect …
[HTML][HTML] Contributions of PTSD polygenic risk and environmental stress to suicidality in preadolescents
Suicidal ideation and attempts (ie, suicidality) are complex behaviors driven by
environmental stress, genetic susceptibility, and their interaction. Preadolescent suicidality is …
environmental stress, genetic susceptibility, and their interaction. Preadolescent suicidality is …