Polyphenols as Potential Geroprotectors

E Proshkina, L Koval, E Platonova… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Currently, a large amount of evidence of beneficial effects of diets enriched
with polyphenols on various aspects of health has been accumulated. These …

[HTML][HTML] Paeonol promotes longevity and fitness in Caenorhabditis elegans through activating the DAF-16/FOXO and SKN-1/Nrf2 transcription factors

R Li, Q Yi, J Wang, Y Miao, Q Chen, Y Xu… - Biomedicine & …, 2024 - Elsevier
Paeonol, as one of the most abundant plant-derived polyphenols, has multiple bioactivities
including anti-inflammatory, anti-tumor, and anti-cardiovascular diseases. Nevertheless, the …

Aquilaria crassna Leaf Extract Ameliorates Glucose-Induced Neurotoxicity In Vitro and Improves Lifespan in Caenorhabditis elegans

N Pattarachotanant, N Sornkaew, W Warayanon… - Nutrients, 2022 - mdpi.com
Hyperglycemia is one of the important causes of neurodegenerative disorders and aging.
Aquilaria crassna Pierre ex Lec (AC) has been widely used to relieve various health …

[HTML][HTML] Longevity-associated transcription factor ATF7 promotes healthspan by suppressing cellular senescence and systematic inflammation

Y Huang, MX Ge, YH Li, JL Li, Q Yu, FH Xiao… - Aging and …, 2023 - ncbi.nlm.nih.gov
Aging is characterized by persistent low-grade systematic inflammation, which is largely
responsible for the occurrence of various age-associated diseases. We and others have …

[HTML][HTML] Research progress on the relationship between Paneth cells-susceptibility genes, intestinal microecology and inflammatory bowel disease

QM Zhou, L Zheng - World Journal of Clinical Cases, 2023 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a disorder of the immune system and intestinal
microecosystem caused by environmental factors in genetically susceptible people. Paneth …

Leveraging a Y. lipolytica naringenin chassis for biosynthesis of apigenin and associated glucoside

CB Marsan, SG Lee, A Nguyen, ARG Sierra… - Metabolic …, 2024 - Elsevier
Flavonoids are a diverse set of natural products with promising bioactivities including anti-
inflammatory, anti-cancer, and neuroprotective properties. Previously, the oleaginous host …

Molecular mechanism of culinary herb Artemisia argyi in promoting lifespan and stress tolerance

J Wang, D Zhu, H Cui, Y Xu, S Shang, Y Miao, Z Xu… - npj Science of …, 2024 - nature.com
Artemisia argyi Lévl. et Vant.(A. argyi) leaf possesses various health promoting functions
contributed by its main bioactive flavonoids. In this study, the anti-aging effect and …

Anti-infective properties of mung bean (Vigna radiata (L.) R. Wilczek) coat extract on Pseudomonas aeruginosa-infected Caenorhabditis elegans: Transcriptomics and …

M Tao, Y Huang, T Xu, X Peng, X Liao, Z Xia… - Journal of …, 2025 - Elsevier
Ethnopharmacological relevance Mung bean coat has long been known for its wide-ranging
health benefits, including antibacterial, anti-inflammatory, and immune-modulatory …

Aged gut microbiota promotes arrhythmia susceptibility via oxidative stress

Z Fu, Y Ying, R Wang, Y Wang - Iscience, 2024 - cell.com
Arrhythmias and sudden cardiac death (SCD) impose a significant burden. Their prevalence
rises with age and is linked to gut dysbiosis. Our study aimed to determine whether aged gut …

Glycoside-metabolizing oxidoreductase D3dgpA from human gut bacterium

H Kim, HTN Mi, JH Ahn, JS Lee, BE Eser… - … in Bioengineering and …, 2024 - frontiersin.org
The Gfo/Idh/MocA family enzyme DgpA was known to catalyze the regiospecific oxidation of
puerarin to 3”-oxo-puerarin in the presence of 3-oxo-glucose. Here, we discovered that …