Mutations in the gene BEST1 are causally associated with as many as five clinically distinct
retinal degenerative diseases, which are collectively referred to as the “bestrophinopathies” …

The past few years have witnessed rapid development of the optoretinogram—a
noninvasive, optical measurement of neural function in the retina, and especially the …

Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal
diabetic neuropathy (RDN), characterized by inner retinal neurodegeneration, also occurs in …

Objective optical assessment of photoreceptor function may permit earlier diagnosis of
retinal disease than current methods such as perimetry, electrophysiology, and clinical …

Vision is the sense that we use to navigate the world around us. Thus it is not surprising that
blindness is one of people's most feared maladies. Heritable diseases of the retina, such as …

Mutations in the BEST1 gene cause detachment of the retina and degeneration of
photoreceptor (PR) cells due to a primary channelopathy in the neighboring retinal pigment …

Purpose.: Quantitative fundus autofluorescence (qAF), spectral domain optical coherence
tomography (SD-OCT) segmentation, and multimodal imaging were performed to elucidate …

Early age-related macular degeneration (AMD) is characterized by degeneration of the
choriocapillaris, the vascular supply of retinal photoreceptor cells. We assessed vascular …

Purpose: To examine outer retinal band changes after flash stimulus and subsequent dark
adaptation with ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods …

Human and animal retinal optical coherence tomography (OCT) images show a
hyporeflective band (HB) between the photoreceptor tip and retinal pigment epithelium …