Antecedents of major depressive, bipolar, and psychotic disorders: a systematic review and meta-analysis of prospective studies

R Uher, B Pavlova, S Najafi, N Adepalli, B Ross… - Neuroscience & …, 2024 - Elsevier
Major depressive, bipolar, or psychotic disorders are preceded by earlier manifestations in
behaviours and experiences. We present a synthesis of evidence on associations between …

Rethinking the first episode of schizophrenia: identifying convergent mechanisms during development and moving toward prediction

JK Forsyth, CE Bearden - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
The neurodevelopmental hypothesis of schizophrenia has long suggested that the cardinal
psychotic symptoms that have traditionally defined the disorder, and which most commonly …

Theory of mind in schizophrenia through a clinical liability approach: a sib-pair study

M Giralt-López, S Miret, S Campanera… - Frontiers in …, 2024 - frontiersin.org
Background Consistent findings indicate that Theory of Mind (ToM) is impaired in
schizophrenia (SZ). To investigate whether such deficits are trait-or state-dependent, we …

[HTML][HTML] Exploring causal mechanisms of psychosis risk

D Oliver, E Chesney, AE Cullen, C Davies… - Neuroscience & …, 2024 - Elsevier
Robust epidemiological evidence of risk and protective factors for psychosis is essential to
inform preventive interventions. Previous evidence syntheses have classified these risk and …

Identifying clinical and proteomic markers for early diagnosis and prognosis prediction of major psychiatric disorders

H Lee, D Han, SJ Rhee, J Lee, J Kim, Y Lee… - Journal of Affective …, 2025 - Elsevier
Background To clarify if blood proteins can predict disease progression among individuals
at clinical high-risk of severe mental illness (CHR-SMI), we developed a statistical model …

Systematic review of clinical prediction models for psychosis in individuals meeting At Risk Mental State criteria

A Hunt, H Law, R Carney, R Mulholland… - Frontiers in …, 2024 - frontiersin.org
Objectives This study aims to review studies developing or validating a prediction model for
transition to psychosis in individuals meeting At Risk Mental State (ARMS) criteria focussing …

Nomenclature for psychosis risk in Japan: Survey results from high-risk individuals, caregivers, and mental health professionals

T Takahashi, N Katagiri, Y Higuchi, S Nishiyama… - Schizophrenia …, 2024 - Elsevier
Background Labeling terms for high-risk state for psychosis, such as 'ultra-high
risk'(UHR),'attenuated psychosis syndrome'(APS), and 'at-risk mental state'(ARMS), have …

Tunisian Adolescents at CHR for Psychosis: A Pilot Study of Cognitive Remediation in a LMIC

Z Abbes, S Taleb, HB Yahia, H Hmidi… - Early Intervention in …, 2024 - Wiley Online Library
Background Clinical high risk (CHR) youth are known to exhibit cognitive deficits at similar
levels to their more severally ill counter parts. Cognitive training (CT) programs offer a …

Individualized pretest risk estimates to guide treatment decisions in patients with clinical high risk for psychotic disorders

E Sprüngli-Toffel, E Studerus, L Curtis… - Spanish Journal of …, 2024 - Elsevier
Introduction Clinical high risk for psychosis (CHR) states are associated with an increased
risk of transition to psychosis. However, the predictive value of CHR screening interviews is …

Early psychosis and early intervention: clinical, functional, and cognitive outcomes

WC Chang, T Nemoto, SKW Chan, CYZ Tang… - Frontiers in …, 2024 - frontiersin.org
Psychotic disorders are a group of severe mental disorders which affects 2-3% of the
population and constitutes one of the leading causes of disability worldwide. Early …