Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

The accumulation of senescent cells can drive many age-associated phenotypes and
pathologies. Consequently, it has been proposed that removing senescent cells might …

The aim of this review is to give an outline of the blood clearance function of the liver
sinusoidal endothelial cells (LSECs) in health and disease. Lining the hundreds of millions …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Background Dysfunction of liver sinusoidal endothelial cells (LSECs) is permissive for the
progression of liver fibrosis and cirrhosis and responsible for its clinical complications. Here …

The incidence of non-alcoholic fatty liver disease (NAFLD) has increased significantly over
the past two decades. NAFLD ranges from simple steatosis (NAFL) to nonalcoholic …

Vaccination has substantially reduced the morbidity and mortality of bacterial diseases, but
mechanisms of vaccine-elicited pathogen clearance remain largely undefined. We report …

Liver sinusoidal endothelial cells (LSECs) are the gatekeeper cells in the liver, contributing
critical roles in liver physiological and pathological changes. Factors such as dietary …

Bacteriophages (phages) are the most abundant biological entity in the human body, but
until recently the role that phages play in human health was not well characterized. Although …