Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
Polycystic ovary syndrome: pathophysiology, presentation, and treatment with emphasis on adolescent girls
SF Witchel, SE Oberfield, AS Peña - Journal of the Endocrine …, 2019 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to 20% of …
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to 20% of …
Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment
E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …
associated with a substantially increased lifetime risk of comorbidities, including type 2 …
Pathophysiological roles of chronic low‐grade inflammation mediators in polycystic ovary syndrome
M Rostamtabar, S Esmaeilzadeh… - Journal of cellular …, 2021 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …
Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
S Patel - The Journal of steroid biochemistry and molecular …, 2018 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine disorder, afflicting females of
reproductive age. This syndrome leads to infertility, insulin resistance, obesity, and …
reproductive age. This syndrome leads to infertility, insulin resistance, obesity, and …
Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome
How obesity and elevated androgen levels in women with polycystic ovary syndrome
(PCOS) affect their offspring is unclear. In a Swedish nationwide register-based cohort and a …
(PCOS) affect their offspring is unclear. In a Swedish nationwide register-based cohort and a …
An international consortium update: pathophysiology, diagnosis, and treatment of polycystic ovarian syndrome in adolescence
L Ibáñez, SE Oberfield, S Witchel, RJ Auchus… - Hormone research in …, 2017 - karger.com
This paper represents an international collaboration of paediatric endocrine and other
societies (listed in the Appendix) under the International Consortium of Paediatric …
societies (listed in the Appendix) under the International Consortium of Paediatric …
Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors
D Szukiewicz, S Trojanowski, A Kociszewska… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains …
reproductive age. Despite its incidence, the syndrome is poorly understood and remains …
Metabolic consequences of obesity and insulin resistance in polycystic ovary syndrome: diagnostic and methodological challenges
YM Jeanes, S Reeves - Nutrition research reviews, 2017 - cambridge.org
Women with polycystic ovary syndrome (PCOS) have a considerable risk of metabolic
dysfunction. This review aims to present contemporary knowledge on obesity, insulin …
dysfunction. This review aims to present contemporary knowledge on obesity, insulin …
Adiponectin protects against development of metabolic disturbances in a PCOS mouse model
A Benrick, B Chanclón, P Micallef… - Proceedings of the …, 2017 - National Acad Sciences
Adiponectin, together with adipocyte size, is the strongest factor associated with insulin
resistance in women with polycystic ovary syndrome (PCOS). This study investigates the …
resistance in women with polycystic ovary syndrome (PCOS). This study investigates the …