miRNA: a promising therapeutic target in cancer
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …
complementarity pairing. Since discovery, they have been reported to be involved in a …
Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy
MJ Ramaiah, AD Tangutur, RR Manyam - Life sciences, 2021 - Elsevier
The role of genetic and epigenetic factors in tumor initiation and progression is well
documented. Histone deacetylases (HDACs), histone methyl transferases (HMTs), and DNA …
documented. Histone deacetylases (HDACs), histone methyl transferases (HMTs), and DNA …
Circular RNAs: biogenesis, function and role in human diseases
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
miRNAs as potential game-changers in melanoma: a comprehensive review
Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …
Clustered miRNAs and their role in biological functions and diseases
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
Improved loading of plasma-derived extracellular vesicles to encapsulate antitumor miRNAs
MAC Pomatto, B Bussolati, S D'Antico, S Ghiotto… - … Therapy-Methods & …, 2019 - cell.com
Extracellular vesicles (EVs) carry various molecules involved in intercellular communication
and have raised great interest as drug delivery systems. Several engineering methods have …
and have raised great interest as drug delivery systems. Several engineering methods have …
[HTML][HTML] Circular RNAs as potential biomarkers for cancer diagnosis and therapy
F Wang, AJ Nazarali, S Ji - American journal of cancer research, 2016 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a naturally occurring type of universal and diverse
endogenous noncoding RNAs which unlike linear RNAs, have covalently linked ends. They …
endogenous noncoding RNAs which unlike linear RNAs, have covalently linked ends. They …
Familial hypercholesterolemia: the most frequent cholesterol metabolism disorder caused disease
A Benito-Vicente, KB Uribe, S Jebari… - International journal of …, 2018 - mdpi.com
Cholesterol is an essential component of cell barrier formation and signaling transduction
involved in many essential physiologic processes. For this reason, cholesterol metabolism …
involved in many essential physiologic processes. For this reason, cholesterol metabolism …
The roles of different microRNAs in the regulation of cholesterol in viral hepatitis
X Meng, Y Eslami, E Derafsh, A Saihood… - Cell Communication and …, 2023 - Springer
Cholesterol plays a significant role in stabilizing lipid or membrane rafts, which are specific
cellular membrane structures. Cholesterol is involved in numerous cellular processes …
cellular membrane structures. Cholesterol is involved in numerous cellular processes …
MicroRNA biogenesis, gene silencing mechanisms and role in breast, ovarian and prostate cancer
Micro-ribonucleic acids (miRNAs) are important class of short regulatory RNA molecules
involved in regulation of several essential biological processes. In addition to Dicer and …
involved in regulation of several essential biological processes. In addition to Dicer and …