This review focuses on DNA damage caused by a variety of oxidizing, alkylating, and
nitrating species, and it may play an important role in the pathophysiology of inflammation …

Hydroxyl radical (HO•) is the most reactive toward DNA among the reactive oxygen species
(ROS) generated in aerobic organisms by cellular metabolisms. HO• is generated also by …

We examined the reaction of hydroxyl radicals (HO•) and sulfate radical anions (SO4•−),
which is generated by ionizing radiation in aqueous solutions under anoxic conditions, with …

Product analysis from the iron Fenton oxidation of 2′-deoxyguanosine found reactions in
bicarbonate buffer yield 8-oxo-2′-deoxyguanosine and spiroiminodihyantoin consistent …

Radical reactions in water or aqueous media are important for organic synthesis, realizing
high-yielding processes under non-toxic and environmentally friendly conditions. This …

The consequences of aging and disease conditions in tissues involve reactive oxygen
species (ROS) and related molecular alterations of different cellular compartments. We …

Mitochondrial (mt) DNA and nuclear (n) DNA have known structures and roles in cells;
however, they are rarely compared under specific conditions such as oxidative or …

In recent years, nucleic acids have emerged as powerful biomaterials, revolutionizing the
field of biomedicine. This review explores the multifaceted applications of nucleic acids …

Cockayne Syndrome (CS) is an autosomal recessive neurodegenerative premature aging
disorder associated with defects in nucleotide excision repair (NER). Cells from CS patients …

One of the most distinguished features in biological effects of heavy ions would be the
decrease of oxygen effect in the high-LET region. This feature has been referred to as the …